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Gene Expression Data
Assay Details
Assay
Reference: J:303151 Funato Y, et al., Renal function of cyclin M2 Mg2+ transporter maintains blood pressure. J Hypertens. 2017 Mar;35(3):585-592
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6696057
Gene symbol: Slc12a3
Gene name: solute carrier family 12, member 3
Antibody: anti-NCC
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 2c +/+: embryonic day 18.5 (more )
Note: Double labeled: red - Slc12a3; green - Cnnm2 (assay MGI:6696056)
Structure Level Pattern Image Note
TS26: distal convoluted tubule Present Regionally restricted 2c merge +/+ , 2c NCC +/+ Expression is seen in the apical membrane.
Specimen 2c d/d: embryonic day 18.5; Cnnm2tm1.1Hmik/Cnnm2tm1.1Hmik (more )
Note: Double labeled: red - Slc12a3; green - Cnnm2 (assay MGI:6696056)
Structure Level Pattern Image Note
TS26: distal convoluted tubule Present Regionally restricted 2c NCC d/d , 2c merge d/d Expression is seen in the apical membrane.
Specimen 3b +/+ (Six2-Cre): postnatal month 2; Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Double labeled: red - Slc12a3; green - Cnnm2 (assay MGI:6696056)
Structure Level Pattern Image Note
TS28: distal convoluted tubule Present Regionally restricted 3b merge +/+; cre , 3b NCC +/+; cre Expression is seen in the apical membrane.
Specimen 3b fl/fl (Six2-Cre): postnatal month 2; Cnnm2tm1Hmik/Cnnm2tm1Hmik, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Double labeled: red - Slc12a3; green - Cnnm2 (assay MGI:6696056)
Structure Level Pattern Image Note
TS28: distal convoluted tubule Present Regionally restricted 3b merge fl/fl; cre , 3b NCC fl/fl; cre Expression is seen in the apical membrane.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory