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Gene Expression Data
Assay Details
Assay
Reference: J:231231 Abby E, et al., Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts. Nat Commun. 2016;7:10324
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6695312
Gene symbol: Meioc
Gene name: meiosis specific with coiled-coil domain
Antibody: Anti-Meioc
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: Two antibodies were described MGI:6694233 and MGI:6694235; either could have been used in this assay.
Results
Specimen 1d: postnatal adult (more )
Note: Double labeled: green - Meioc; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: testis Present Regionally restricted 1d Meioc , 1d merge Expression was detected in the cytoplasmic compartment of meiocytes.
Specimen 1e: embryonic day 15.5 (more )
Note: Double labeled: green - Meioc; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS23: ovary Present Regionally restricted 1e Meioc , 1e merge Expression was detected in the cytoplasmic compartment of meiocytes.
Specimen 2a: postnatal day 8 (more )
Note: Double labeled: green - Meioc; red - Stra8 (assay MGI:6695333).
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted 2a top , 2a bottom In the postnatal testis, 88% of the Stra8-positive cells also expressed Meioc, indicating Meioc was present at the onset of meiosis.
Specimen 2b Prelepto: postnatal (more )
Note: Preleptotene. Double labeled: green - Meioc; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: spermatocyte Present 2b Prelepto merge , 2b Prelepto Meioc
Specimen 2b Lepto: postnatal (more )
Note: Leptotene. Double labeled: green - Meioc; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: spermatocyte Present 2b Lepto Meioc , 2b Lepto merge
Specimen 2b Zygo: postnatal (more )
Note: Zygotene. Double labeled: green - Meioc; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: spermatocyte Present 2b Zygo merge , 2b Zygo Meioc
Specimen 2b Pachy: postnatal (more )
Note: Pachytene. Double labeled: green - Meioc; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: spermatocyte Present 2b Pachy Meioc , 2b Pachy merge
Specimen 2b Diplo: postnatal (more )
Note: Diplotene. Double labeled: green - Meioc; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: spermatocyte Present 2b Diplo merge , 2b Diplo Meioc
Specimen 2b Zygo-like: postnatal; Meioctm1a(KOMP)Wtsi/Meioctm1a(KOMP)Wtsi (more )
Note: Zygotene-like. Double labeled: green - Meioc; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: spermatocyte Absent 2b Zygo-like Meioc , 2b Zygo-like merge
Specimen S3b right: postnatal day 16 (more )
Note: Double labeled: green - Meioc; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: testis Present S3b right
Specimen S3c Meioc+/+: embryonic day 15.5 (more )
Note: Double labeled: green - Meioc; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS23: meiotic germ cell of ovary Present S3c Meioc+/+
Specimen S3c Meioc-/-: embryonic day 15.5; Meioctm1a(KOMP)Wtsi/Meioctm1a(KOMP)Wtsi (more )
Note: Double labeled: green - Meioc; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS23: meiotic germ cell of ovary Absent S3c Meioc-/-
Specimen S3c Meioc+/+ Lepto: embryonic day 15.5 (more )
Note: Double labeled: green - Meioc; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS23: meiotic germ cell of ovary Present S3c Lepto
Specimen S3c Meioc+/+ Zygo: embryonic day 15.5 (more )
Note: Double labeled: green - Meioc; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS23: meiotic germ cell of ovary Present S3c Zygo
Specimen S3c Meioc+/+ Pachy: embryonic day 15.5 (more )
Note: Double labeled: green - Meioc; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS23: meiotic germ cell of ovary Present S3c Pachy
Specimen S3c Meioc+/+ Diplo: embryonic day 18.5 (more )
Note: Double labeled: green - Meioc; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS26: meiotic germ cell of ovary Present S3c Diplo
Specimen S3c Meioc-/- Lepto-like: embryonic day 15.5; Meioctm1a(KOMP)Wtsi/Meioctm1a(KOMP)Wtsi (more )
Note: Double labeled: green - Meioc; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS23: meiotic germ cell of ovary Absent S3c Lepto-like
Specimen S3c Meioc-/- Zygo-like: embryonic day 18.5; Meioctm1a(KOMP)Wtsi/Meioctm1a(KOMP)Wtsi (more )
Note: Double labeled: green - Meioc; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS26: meiotic germ cell of ovary Absent S3c Zygo-like
Specimen S3d Meioc+/+: postnatal adult (more )
Note: Double labeled: green - Meioc; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: testis Present S3d Meioc+/+
Specimen S3d Meioc-/-: postnatal adult; Meioctm1a(KOMP)Wtsi/Meioctm1a(KOMP)Wtsi (more )
Note: Double labeled: green - Meioc; red - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: testis Absent S3d Meioc-/-
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory