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Gene Expression Data
Assay Details
Assay
Reference: J:295322 Kopp ND, et al., Functions of Gtf2i and Gtf2ird1 in the developing brain: transcription, DNA binding and long-term behavioral consequences. Hum Mol Genet. 2020 Jun 3;29(9):1498-1519
Assay type: Western blot
MGI Accession ID: MGI:6694256
Gene symbol: Gtf2i
Gene name: general transcription factor II I
Results Image: 6C GTF2I
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex
WT E9.5 TS15: future brain Present FVB(129P2)-Pde6b+ Tyrc-ch/Mmjax Not Specified
Gtf2i+/-;Gtf2ird1+/- E9.5 TS15: future brain Weak (a) FVB(129P2)-Pde6b+ Gtf2iem2Jdd Gtf2ird1em2Jdd Tyrc-ch/Mmjax Gtf2iem2Jdd/Gtf2i+, Gtf2ird1em2Jdd/Gtf2ird1+Not Specified
Gtf2i-/-;Gtf2ird1-/- E9.5 TS15: future brain Absent (b) FVB(129P2)-Pde6b+ Gtf2iem2Jdd Gtf2ird1em2Jdd Tyrc-ch/Mmjax Gtf2iem2Jdd/Gtf2iem2Jdd, Gtf2ird1em2Jdd/Gtf2ird1em2JddNot Specified
WT E9.5 TS15: future brain Present FVB(129P2)-Pde6b+ Tyrc-ch/Mmjax Not Specified
Gtf2i+/-;Gtf2ird1+/- E9.5 TS15: future brain Weak (a) FVB(129P2)-Pde6b+ Gtf2iem2Jdd Gtf2ird1em2Jdd Tyrc-ch/Mmjax Gtf2iem2Jdd/Gtf2i+, Gtf2ird1em2Jdd/Gtf2ird1+Not Specified
Gtf2i-/-;Gtf2ird1-/- E9.5 TS15: future brain Absent (b) FVB(129P2)-Pde6b+ Gtf2iem2Jdd Gtf2ird1em2Jdd Tyrc-ch/Mmjax Gtf2iem2Jdd/Gtf2iem2Jdd, Gtf2ird1em2Jdd/Gtf2ird1em2JddNot Specified
WT E9.5 TS15: future brain Present FVB(129P2)-Pde6b+ Tyrc-ch/Mmjax Not Specified
Gtf2i+/-;Gtf2ird1+/- E9.5 TS15: future brain Weak (a) FVB(129P2)-Pde6b+ Gtf2iem2Jdd Gtf2ird1em2Jdd Tyrc-ch/Mmjax Gtf2iem2Jdd/Gtf2i+, Gtf2ird1em2Jdd/Gtf2ird1+Not Specified
Gtf2i-/-;Gtf2ird1-/- E9.5 TS15: future brain Absent (b) FVB(129P2)-Pde6b+ Gtf2iem2Jdd Gtf2ird1em2Jdd Tyrc-ch/Mmjax Gtf2iem2Jdd/Gtf2iem2Jdd, Gtf2ird1em2Jdd/Gtf2ird1em2JddNot Specified
Notes:
(a) The two base pair deletion decreased protein by 50% in heterozygous mutants.
(b) No protein is detected in homozygous mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory