Gtf2ird1 Western blot Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:295322 Kopp ND, et al., Functions of Gtf2i and Gtf2ird1 in the developing brain: transcription, DNA binding and long-term behavioral consequences. Hum Mol Genet. 2020 Jun 3;29(9):1498-1519
Assay type:	Western blot
MGI Accession ID:	MGI:6694253
Gene symbol:	Gtf2ird1
Gene name:	general transcription factor II I repeat domain-containing 1

Antibody:

GTF2IRD1 antibody (NBP1-91973)

Results

Image: 4E GTF2IRD1

	Sample Information		Bands	Other Sample Information
Lane	Age	Structure	Size Not Specified	Genetic Background	Mutant Allele(s)	Sex
WT	E9.5	TS15: future brain	Present	FVB(129P2)-Pde6b⁺ Tyr^c-ch/Mmjax		Not Specified
Gtf2ird1+/-	E9.5	TS15: future brain	Present (a)	FVB(129P2)-Pde6b⁺ Gtf2ird1^em3Jdd Tyr^c-ch/Mmjax	Gtf2ird1^em3Jdd/Gtf2ird1⁺	Not Specified
Gtf2ird1-/-	E9.5	TS15: future brain	Weak (b)	FVB(129P2)-Pde6b⁺ Gtf2ird1^em3Jdd Tyr^c-ch/Mmjax	Gtf2ird1^em3Jdd/Gtf2ird1^em3Jdd	Not Specified
WT	E9.5	TS15: future brain	Present	FVB(129P2)-Pde6b⁺ Tyr^c-ch/Mmjax		Not Specified
Gtf2ird1+/-	E9.5	TS15: future brain	Present (a)	FVB(129P2)-Pde6b⁺ Gtf2ird1^em3Jdd Tyr^c-ch/Mmjax	Gtf2ird1^em3Jdd/Gtf2ird1⁺	Not Specified
Gtf2ird1-/-	E9.5	TS15: future brain	Weak (b)	FVB(129P2)-Pde6b⁺ Gtf2ird1^em3Jdd Tyr^c-ch/Mmjax	Gtf2ird1^em3Jdd/Gtf2ird1^em3Jdd	Not Specified
WT	E9.5	TS15: future brain	Present	FVB(129P2)-Pde6b⁺ Tyr^c-ch/Mmjax		Not Specified
Gtf2ird1+/-	E9.5	TS15: future brain	Present (a)	FVB(129P2)-Pde6b⁺ Gtf2ird1^em3Jdd Tyr^c-ch/Mmjax	Gtf2ird1^em3Jdd/Gtf2ird1⁺	Not Specified
Gtf2ird1-/-	E9.5	TS15: future brain	Weak (b)	FVB(129P2)-Pde6b⁺ Gtf2ird1^em3Jdd Tyr^c-ch/Mmjax	Gtf2ird1^em3Jdd/Gtf2ird1^em3Jdd	Not Specified

Notes:
(a) No significant difference between wild type and heterozygous mutants.
(b) Protein reduced in homozygous mutants compared to wild type, with a slight shift to a lower molecular weight.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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