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Gene Expression Data
Assay Details
Assay
Reference: J:250135 Ding M, et al., Purkinje Cell Degeneration and Motor Coordination Deficits in a New Mouse Model of Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay. Front Mol Neurosci. 2017;10:121
Assay type: RT-PCR
MGI Accession ID: MGI:6515816
Gene symbol: Ntf3
Gene name: neurotrophin 3
Probe: NT-3-pA, NT-3-pB
Assay notes: Quantitative RT-PCR. Gapdh was used as an internal control.
Results
Image: 5D NT-3 ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Amount Genetic BackgroundMutant Allele(s)Sex
P7 WT P7 TS28: cerebellum Present Not Specified; total RNA C57BL/6 Not Specified
P7 Ankfy1/+ P7 TS28: cerebellum Present Not Specified; total RNA B6.129P2-Ankfy1Gt(RRE069)Byg Ankfy1Gt(RRE069)Byg/Ankfy1+Not Specified
P14 WT P14 TS28: cerebellum Present Not Specified; total RNA C57BL/6 Not Specified
P14 Ankfy1/+ P14 TS28: cerebellum Present Not Specified; total RNA B6.129P2-Ankfy1Gt(RRE069)Byg Ankfy1Gt(RRE069)Byg/Ankfy1+Not Specified
P21 WT P21 TS28: cerebellum Present Not Specified; total RNA C57BL/6 Not Specified
P21 Ankfy1/+ P21 TS28: cerebellum Present Not Specified; total RNA B6.129P2-Ankfy1Gt(RRE069)Byg Ankfy1Gt(RRE069)Byg/Ankfy1+Not Specified
P30 WT P30 TS28: cerebellum Present Not Specified; total RNA C57BL/6 Not Specified
P30 Ankfy1/+ P30 TS28: cerebellum Present Not Specified; total RNA B6.129P2-Ankfy1Gt(RRE069)Byg Ankfy1Gt(RRE069)Byg/Ankfy1+Not Specified
Notes:
(a) Ntf3 expression began to increase on P7 in Ankfy1/+ mice and surpassed the expression observed in wild type mice beginning on P14. A significant difference was observed between wild type and Ankfy1/+ at P21.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory