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Gene Expression Data
Assay Details
Assay
Reference: J:116706 Zhao ZQ, et al., Lmx1b is required for maintenance of central serotonergic neurons and mice lacking central serotonergic system exhibit normal locomotor activity. J Neurosci. 2006 Dec 6;26(49):12781-8
Assay type: RNA in situ
MGI Accession ID: MGI:6512030
Gene symbol: Lmx1b
Gene name: LIM homeobox transcription factor 1 beta
Probe: Lmx1b probe13
Probe preparation: Antisense RNA
Results
Specimen 2G: embryonic day 11.5 (more )
Note: rostral part of the hindbrain
Structure Level Pattern Image Note
TS19: hindbrain floor plate Present 2G
TS19: hindbrain lateral wall Present Regionally restricted 2G Expressed in 5-HT neurons in the rostral part.
Specimen 2H: embryonic day 11.5; Lmx1btm1Zfc/Lmx1btm1Zfc, Tg(Fev-cre)1Esd/0 (more )
Note: Conditional mutant. rostral part of the hindbrain
Structure Level Pattern Image Note
TS19: hindbrain floor plate Present 2H Similar expression patterns compared with wild-type mice.
TS19: hindbrain lateral wall Present Regionally restricted 2H Similar expression patterns in 5-HT neurons in the rostral part, compared with wild-type mice.
Specimen not shown: embryonic day 11.5 (more )
Note: caudal part of the hindbrain
Structure Level Pattern Image Note
TS19: hindbrain Present Expressed in the caudal part.
Specimen not shown: embryonic day 11.5; Lmx1btm1Zfc/Lmx1btm1Zfc, Tg(Fev-cre)1Esd/0 (more )
Note: Conditional mutant. caudal part of the hindbrain
Structure Level Pattern Image Note
TS19: hindbrain Present Similar expression patterns in the caudal part compared with wild-type mice.
Specimen 3M: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hindbrain Present 3M
Specimen 3N: embryonic day 14.5; Lmx1btm1Zfc/Lmx1btm1Zfc, Tg(Fev-cre)1Esd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: hindbrain Weak 3N Highly reduced expression compared with the wild-type.
Specimen 5A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hindbrain Present 5A
Specimen 5B: embryonic day 14.5; Fevtm1Esd/Fevtm1Esd (more )
Structure Level Pattern Image Note
TS22: hindbrain Present 5B Similar as in the wild-type.
Specimen not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hindbrain Present
Specimen not shown: embryonic day 16.5; Lmx1btm1Zfc/Lmx1btm1Zfc, Tg(Fev-cre)1Esd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: hindbrain Trace Rarely detected in the mutant.
Specimen not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hindbrain Present
Specimen not shown: embryonic day 16.5; Fevtm1Esd/Fevtm1Esd (more )
Structure Level Pattern Image Note
TS24: hindbrain Present Similar as in the wild-type.
Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: raphe nucleus Present
Specimen not shown: postnatal adult; Lmx1btm1Zfc/Lmx1btm1Zfc, Tg(Fev-cre)1Esd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: raphe nucleus Trace Virtually absent in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory