Gene Expression Data
Assay Details
Assay
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Reference:
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J:63529
Fang C, et al., Molecular cloning, sequencing, and tissue and developmental expression of mouse cartilage oligomeric matrix protein (COMP). J Orthop Res. 2000 Jul;18(4):593-603
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6507718
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Gene symbol:
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Comp
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Gene name:
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cartilage oligomeric matrix protein
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Antibody:
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anti-Comp
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
6A:
embryonic day 10.0
(more )
Specimen
6A:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS16: trunk mesenchyme |
Present |
Regionally restricted |
6B
,
6A
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Expression is in predifferentiated mesenchyme alongside the neural tube.
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Specimen
7A:
embryonic day 13.0
(more )
Specimen
7A:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 13.0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Specimen
7C:
embryonic day 13.0
(more )
Specimen
7C:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 13.0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: limb cartilage condensation |
Present |
Regionally restricted |
7C
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Expression is in hypertrophic chondrocytes of the precartilagenous condensations.
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Specimen
8A:
embryonic day 19.0
(more )
Specimen
8A:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 19.0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: vertebral cartilage condensation |
Present |
Regionally restricted |
8B
,
8A
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Expression is localized to the pericellular region and territorial extracellular matrix of hypertrophic chondrocytes and is weak in the proliferating chondrocytes in the growth zone of vertebral bodies. Expression is absent in the resting zone adjacent to the vertebral disc.
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Specimen
8C:
embryonic day 19.0
(more )
Specimen
8C:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 19.0
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: perichondrium |
Present |
|
8C
,
8D
|
|
TS26: periosteum |
Present |
|
8C
,
8D
|
|
TS26: articular cartilage |
Present |
Regionally restricted |
8D
,
8C
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Expression is in the superficial layer of the articular surface. Expression is stronger in the pericellular region and territorial matrix of the hypertrophic zone and weaker in the proliferative zone and is absent in the resting zone of the humerus.
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TS26: humerus |
Present |
Regionally restricted |
8C
,
8D
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Expression is stronger in the pericellular region and territorial matrix of the hypertrophic zone and weaker in the proliferative zone and in the calcified matrix, and is absent in the resting zone and in the central areas of epiphyseal cartilage.
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Specimen
not shown E16:
embryonic day 16.0
(more )
Specimen
not shown E16:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 16.0
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Sex:
|
Not Specified
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Type:
|
section
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Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Paraffin
|
|