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Gene Expression Data
Assay Details
Assay
Reference: J:213694 Cantu C, et al., Pax6-dependent, but beta-catenin-independent, function of Bcl9 proteins in mouse lens development. Genes Dev. 2014 Sep 1;28(17):1879-84
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6506824
Gene symbol: Bcl9l
Gene name: B cell CLL/lymphoma 9-like
Antibody: anti-Bcl9l
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 4D WT: embryonic day 10.5 (more )
Note: Double labeled: red - Bcl9l; blue - DAPI.
Structure Level Pattern Image Note
TS17: head surface ectoderm Strong Regionally restricted 4D WT Highly expressed in invaginating head surface ectoderm.
TS17: lens pit Present 4D WT
Specimen 4D Pax6-Sey: embryonic day 10.5; Pax6Sey/Pax6Sey (more )
Note: Double labeled: red - Bcl9l; blue - DAPI.
Structure Level Pattern Image Note
TS17: head surface ectoderm Weak 4D Pax6-Sey Ectodermal expression strongly reduced compared with wild-type embryos.
Specimen S4 Bcl9l-IF E10.5: embryonic day 10.5 (more )
Note: Triple labeled: red - Bcl9l; green - Ctnnb1 (assay MGI:6506826); blue - DAPI.
Structure Level Pattern Image Note
TS17: lens vesicle Present S4_Bcl9l - IF 10.5 dpc
Specimen S4 Bcl9l-IF E13.5: embryonic day 13.5 (more )
Note: Triple labeled: red - Bcl9l; green - Ctnnb1 (assay MGI:6506826); blue - DAPI.
Structure Level Pattern Image Note
TS21: lens Strong S4_Bcl9 - IHC 13.5 dpc Expression highly present throughout development specifically in the lens.
Specimen S4 Bcl9l-IF E15.5: embryonic day 15.5 (more )
Note: Triple labeled: red - Bcl9l; green - Ctnnb1 (assay MGI:6506826); blue - DAPI.
Structure Level Pattern Image Note
TS23: lens Strong S4_Bcl9 - IHC 15.5 dpc Expression highly present throughout development specifically in the lens.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory