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Tubb2bem1Rstot
Endonuclease-mediated Allele Detail
Summary
Symbol: Tubb2bem1Rstot
Name: tubulin, beta 2B class IIB; endonuclease-mediated mutation 1, Rolf Stottmann
MGI ID: MGI:6506266
Synonyms: Tubb2bd4185
Gene: Tubb2b  Location: Chr13:34310991-34314337 bp, - strand  Genetic Position: Chr13, 14.04 cM, cytoband A4
Alliance: Tubb2bem1Rstot page
Mutation
origin
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCRISPR/cas9 mediated recombination created a 4,185 bp deletion encompassing the genomic region Chr13:34,126,374-34,130,558 (GRCm38/mm10). (J:278765)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tubb2b Mutation:  21 strains or lines available
References
Original:  J:278765 Bittermann E, et al., Differential requirements of tubulin genes in mammalian forebrain development. PLoS Genet. 2019 Aug;15(8):e1008243
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory