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Gene Expression Data
Assay Details
Assay
Reference: J:94923 Schurov IL, et al., Expression of disrupted in schizophrenia 1 (DISC1) protein in the adult and developing mouse brain indicates its role in neurodevelopment. Mol Psychiatry. 2004 Dec;9(12):1100-10
Assay type: Western blot
MGI Accession ID: MGI:6504903
Gene symbol: Disc1
Gene name: disrupted in schizophrenia 1
Results Image: 6a
 Sample Information Bands Other Sample Information
Lane AgeStructure 105 kDa (a) 100 kDa (b) 75 kDa (c) 71 kDa (d) Genetic BackgroundMutant Allele(s)Sex
O1 P1 TS27: brain Weak Weak Present Weak Not Specified Not Specified
P2 P2 TS27: brain Weak Weak Present Weak Not Specified Not Specified
P3 P3 TS27: brain Weak Weak Present Weak Not Specified Not Specified
P4 P4 TS28: brain Weak Present Present Weak Not Specified Not Specified
P5 P5 TS28: brain Weak Present Present Weak Not Specified Not Specified
P6 P6 TS28: brain Weak Present Present Weak Not Specified Not Specified
P7 P7 TS28: brain Weak Present Present Weak Not Specified Not Specified
P8 P8 TS28: brain Weak Present Present Weak Not Specified Not Specified
P9 P9 TS28: brain Weak Present Present Weak Not Specified Not Specified
P10 P10 TS28: brain Weak Present Present Weak Not Specified Not Specified
P11 P11 TS28: brain Weak Present Present Weak Not Specified Not Specified
P12 P12 TS28: brain Weak Present Present Weak Not Specified Not Specified
P13 P13 TS28: brain Weak Present Present Weak Not Specified Not Specified
P14 P14 TS28: brain Weak Present Present Weak Not Specified Not Specified
P15 P15 TS28: brain Weak Present Present Weak Not Specified Not Specified
P20 P20 TS28: brain Weak Present Present Weak Not Specified Not Specified
P25 P25 TS28: brain Weak Present Present Strong (e) Not Specified Not Specified
P30 P30 TS28: brain Weak Present Present Strong Not Specified Not Specified
P35 P35 TS28: brain Weak Very strong (f) Present Strong Not Specified Not Specified
6M P m 6 TS28: brain Weak Very strong (g) Present Strong (h) Not Specified Not Specified
Notes:
(a) Labeled band 1. Low level of expression at all time points.
(b) Labeled band 2.
(c) Labeled band 3.
(d) Labeled band 4. Lower level of expression during neonatal and early postnatal periods.
(e) Expression upregulated at P25.
(f) Second peak of expression at P35
(g) Expression remains high through 6 months of age.
(h) Expression remains high throughout 6 monts of age.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory