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Gene Expression Data
Assay Details
Assay
Reference: J:90568 Relaix F, et al., Divergent functions of murine Pax3 and Pax7 in limb muscle development. Genes Dev. 2004 May 1;18(9):1088-105
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6488462
Gene symbol: Pax7
Gene name: paired box 7
Reporter: lacZ
Direct Detection
Results
Specimen 1C: embryonic day 10.5; Pax7tm2Pgr/Pax7+ (more )
Structure Level Pattern Image Note
TS17: dermomyotome Present Regionally restricted 1C Expression in dermomyotome, mainly restricted to central region, and excluded from epaxial and hypaxial extremities. No expression in muscle progenitor cells mgrating to hypoglossal chord.
TS17: fronto-nasal process Present 1C
TS17: neural tube Present 1C
TS17: limb mesenchyme Absent 1C No expression in muscle progenitor cells migrating to limb.

Specimen 1D: embryonic day 10.5; Pax7tm2Pgr/Pax7tm2Pgr (more )
Structure Level Pattern Image Note
TS17: dermomyotome Present Regionally restricted 1D Normal distribution of expressing cells in somite.
TS17: fronto-nasal process Present 1D Authors state embryos do not present any obvious defects at sites of Pax7 expression.
TS17: neural tube Present 1D Authors state embryos do not present any obvious defects at sites of Pax7 expression.

Specimen 1G: embryonic day 13.5; Pax7tm2Pgr/Pax7+ (more )
Structure Level Pattern Image Note
TS21: limb muscle Present Regionally restricted 1G Expression in muscle masses of limb as well as trunk.
TS21: trunk musculature Present Regionally restricted 1G Expression in muscle masses of limb as well as trunk.
TS21: cranial muscle Present Regionally restricted 1G Expression in facial muscles.

Specimen 1H: embryonic day 13.5; Pax7tm2Pgr/Pax7tm2Pgr (more )
Structure Level Pattern Image Note
TS21: limb muscle Present Regionally restricted 1H Lack of Pax7 does not lead to any obvious defect. Trunk muscles develope normally.
TS21: trunk musculature Present Regionally restricted 1H Lack of Pax7 does not lead to any obvious defect. Trunk muscles develope normally.
TS21: cranial muscle Present Regionally restricted 1H Expression in facial muscles.

Specimen 1S: embryonic day 11.5; Pax7tm2Pgr/Pax7+ (more )
Structure Level Pattern Image Note
TS19: face Present Regionally restricted 1S Expression in facial muscles not affected.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory