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Gene Expression Data
Assay Details
Assay
Reference: J:275665 Wang LW, et al., Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage. Matrix Biol. 2019 Apr;77:117-128
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6479138
Gene symbol: Fbn2
Gene name: fibrillin 2
Antibody: Anti-Fibrillin 2
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 4 Adamts10+/+ 8 days: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: extracellular matrix Ambiguous 4_8 days Adamts10+/+ center
TS28: vitreous humour Ambiguous 4_8 days Adamts10+/+ center

Specimen 4 Adamts10-/- 8 days: postnatal day 8; Adamts10tm1Dgen/Adamts10tm1Dgen (more )
Structure Level Pattern Image Note
TS28: extracellular matrix Present Regionally restricted 4_8 days Adamts10-/- center Persistent fibril staining was observed in the vitreous in the presumed remnants of the hyaloid vessel matrix in Adamts10-/- eyes.
TS28: vitreous humour Present Regionally restricted 4_8 days Adamts10-/- center Persistent fibril staining was observed in the vitreous in the presumed remnants of the hyaloid vessel matrix in Adamts10-/- eyes.

Specimen 4 Adamts10+/+ 24 days: postnatal day 24 (more )
Structure Level Pattern Image Note
TS28: extracellular matrix Ambiguous 4_24 days Adamts10+/+ center
TS28: vitreous humour Ambiguous 4_24 days Adamts10+/+ center

Specimen 4 Adamts10-/- 24 days: postnatal day 24; Adamts10tm1Dgen/Adamts10tm1Dgen (more )
Structure Level Pattern Image Note
TS28: extracellular matrix Present Regionally restricted 4_24 days Adamts10-/- center Persistent fibril staining was observed in the vitreous in the presumed remnants of the hyaloid vessel matrix in Adamts10-/- eyes.
TS28: vitreous humour Present Regionally restricted 4_24 days Adamts10-/- center Persistent fibril staining was observed in the vitreous in the presumed remnants of the hyaloid vessel matrix in Adamts10-/- eyes.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory