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Gene Expression Data
Assay Details
Assay
Reference: J:143548 Himes AD, et al., Premature differentiation and aberrant movement of pituitary cells lacking both Hes1 and Prop1. Dev Biol. 2009 Jan 1;325(1):151-61
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6471720
Gene symbol: Lhx3
Gene name: LIM homeobox protein 3
Antibody: Lhx3 antibody
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to Cy3
Results
Specimen 5A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: adenohypophysis pars anterior Present Widespread 5A Expression throughout anterior lobe and Rathke's pouch.
TS20: remnant of Rathke's pouch Present Widespread 5A Expression throughout anterior lobe and Rathke's pouch.

Specimen 5B: embryonic day 12.5; Hes1tm1Fgu/Hes1tm1Fgu (more )
Structure Level Pattern Image Note
TS20: adenohypophysis pars anterior Present Widespread 5B Expression throughout anterior lobe and Rathke's pouch.
TS20: remnant of Rathke's pouch Present Widespread 5B Expression throughout anterior lobe and Rathke's pouch.

Specimen 5C: embryonic day 12.5; Prop1df/Prop1df (more )
Structure Level Pattern Image Note
TS20: adenohypophysis pars anterior Present Widespread 5C Expression throughout anterior lobe and Rathke's pouch.
TS20: remnant of Rathke's pouch Present Widespread 5C Expression throughout anterior lobe and Rathke's pouch.

Specimen 5D: embryonic day 12.5; Hes1tm1Fgu/Hes1tm1Fgu, Prop1df/Prop1df (more )
Structure Level Pattern Image Note
TS20: adenohypophysis pars anterior Present Widespread 5D Expression throughout anterior lobe and Rathke's pouch.
TS20: remnant of Rathke's pouch Present Widespread 5D Expression throughout anterior lobe and Rathke's pouch.

Specimen E14.5 Wildtype not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: adenohypophysis pars anterior Present Widespread
TS22: remnant of Rathke's pouch Present Widespread

Specimen E14.5 Hes1 mutant not shown: embryonic day 14.5; Hes1tm1Fgu/Hes1tm1Fgu (more )
Structure Level Pattern Image Note
TS22: adenohypophysis pars anterior Present Widespread Expression not affected by loss of Hes1 or Prop individually or by loss of both at E14.5.
TS22: remnant of Rathke's pouch Present Widespread Expression not affected by loss of Hes1 or Prop individually or by loss of both at E14.5.

Specimen E14.5 Prop1 mutant not shown: embryonic day 14.5; Prop1df/Prop1df (more )
Structure Level Pattern Image Note
TS22: adenohypophysis pars anterior Present Widespread
TS22: remnant of Rathke's pouch Present Widespread

Specimen E14.5 Double mutant not shown: embryonic day 14.5; Hes1tm1Fgu/Hes1tm1Fgu, Prop1df/Prop1df (more )
Structure Level Pattern Image Note
TS22: adenohypophysis pars anterior Present Widespread Expression not affected by loss of Hes1 or Prop individually or by loss of both at E14.5.
TS22: remnant of Rathke's pouch Present Widespread Expression not affected by loss of Hes1 or Prop individually or by loss of both at E14.5.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory