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Gene Expression Data
Assay Details
Assay
Reference: J:94430 De Luca A, et al., Pattern of expression of HtrA1 during mouse development. J Histochem Cytochem. 2004 Dec;52(12):1609-17
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6457117
Gene symbol: Htra1
Gene name: HtrA serine peptidase 1
Antibody: anti-HtrA1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 3A: embryonic day 8.0 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS12: neural ectoderm Strong 3B , 3A Staining seen in neuroepithelial tissues.
TS12: eye neural ectoderm Strong 3A Staining seen in perioptic epithelium.
TS12: alimentary system epithelium Strong 3A , 3B Staining seen in foregut and hindgut epithelium.
TS12: somite Strong 3B , 3A Staining seen in the mesodermal tissues of the somites.
TS12: heart Strong 3A
TS12: vitelline artery Strong 3A , 3B Staining seen in the wall.
TS12: dorsal aorta Strong 3A , 3B Staining seen in the wall.
TS12: allantois Strong Regionally restricted 3A , 3B Staining seen in the base of allantois.

Specimen 3D: embryonic day 12.0 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS20: cerebral cortex Moderate 3D Staining seen in the neopallial cortex/future cerebral cortex.
TS20: midbrain Moderate 3D
TS20: brain Moderate Regionally restricted 3D Staining seen in the epithelium surrounding ventricles, including those surrounding the cerebral ventricles.
TS20: olfactory epithelium Strong 3D
TS20: inner ear epithelium Strong 3D Staining seen in the auditory epithelium.
TS20: cochlea epithelium Strong 3D
TS20: saccule epithelium Strong 3D
TS20: midbrain-hindbrain junction Moderate 3D Staining seen in the pons/midbrain juction.
TS20: spinal cord Moderate 3D Staining seen in the spinal cord canal.
TS20: dorsal root ganglion Strong 3D Staining seen in dorsal and lumbar root ganglia.
TS20: lumbar dorsal root ganglion Strong 3D Staining seen in dorsal and lumbar root ganglia.
TS20: heart Moderate 3D

Specimen 3E: embryonic day 19.0 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS26: brain Moderate 3E
TS26: skin Strong 3E Staining seen in mature and outer layers of stratified epithelium of the skin.
TS26: esophagus epithelium Strong 3E
TS26: intestine epithelium Strong 3E
TS26: urinary system epithelium Strong 3E Staining seen in urinary duct epithelium.
TS26: cardiac muscle tissue Strong 3E
TS26: skeletal muscle tissue Strong 3E Staining seen in striated muscle tissue.
TS26: liver Moderate 3E
TS26: skeleton Present 3E Staining seen in skeletal elements.

Specimen 3F: postnatal day 1 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS27: liver Strong 3F
TS27: cardiac muscle tissue Strong 3F
TS27: skeletal muscle tissue Strong 3F Staining seen in striated muscle.
TS27: spinal cord Strong 3F
TS27: skin Strong 3F Staining seen in the stratified epithelium of skin.
TS27: esophagus epithelium Strong 3F
TS27: intestine epithelium Strong 3F
TS27: brain Moderate 3F
TS27: lung epithelium Moderate 3F
TS27: metanephros epithelium Moderate 3F

Specimen 3G: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: heart Moderate 3G

Specimen not shown: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: cartilage condensation Moderate Staining seen in cartilage primordia of different bones.

Specimen 3H: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: liver Strong 3H

Specimen 3I: embryonic day 19.0 (more )
Structure Level Pattern Image Note
TS26: skin Strong 3I Staining seen in mature and outer layers of skin.

Specimen 3J: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: skin Strong 3J Staining seen in the stratified epithelium of skin.
TS27: hair follicle Strong 3J Staining seen in piliferous follicles.

Specimen 5A: embryonic day 14.5 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS22: corpus striatum Strong 5A , 5B
TS22: olfactory epithelium Present 5A , 5C
TS22: skin Present 5A , 5C
TS22: vomeronasal organ Present 5A , 5C
TS22: nasal septum cartilage Weak 5C , 5A
TS22: tongue muscle Weak 5C , 5A

Specimen 5E: embryonic day 12.0 (more )
Note: longitudinal section
Structure Level Pattern Image Note
TS20: hindbrain Strong Regionally restricted 5E Staining seen in the epithelium surrounding the fourth ventricle.
TS20: cerebral cortex Strong Regionally restricted 5E Staining seen in the epithelium surrounding cerebral ventricles.
TS20: midbrain-hindbrain junction Moderate 5E Staining seen in the pons/midbrain junction.

Specimen 5F: embryonic day 19.0 (more )
Note: longitudinal section
Structure Level Pattern Image Note
TS26: olfactory epithelium Strong 5F


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory