Cldn1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:228856 DiTommaso T, et al., Keratin 76 is required for tight junction function and maintenance of the skin barrier. PLoS Genet. 2014 Oct;10(10):e1004706
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6456592
Gene symbol:	Cldn1
Gene name:	claudin 1

Antibody:	claudin-1 antibody (ab15098)
Assay notes:	Two antibodies were described, but the one used in this assay was not detailed. Claudin-1 antibody MGI:6456184 may have been used in this assay.

Results

5D +/+ ©

Specimen 5D +/+: postnatal adult (more

)
Note: Triple labeled: green - Cldn1; red - ECAD (Cdh1; assay MGI:6696419); blue - DAPI.

Structure	Level	Pattern	Image	Note
TS28: metapodial pad	Present		5D +/+

5D tm1a/tm1a ©

Specimen 5D tm1a/tm1a: postnatal adult; Krt76^{tm1a(KOMP)Wtsi}/Krt76^{tm1a(KOMP)Wtsi} (more

)
Note: Triple labeled: green - Cldn1; red - ECAD (Cdh1; assay MGI:6696419); blue - DAPI.

Structure	Level	Pattern	Image	Note
TS28: metapodial pad	Present	Regionally restricted	5D tm1a/tm1a

5G +/+ ©

Specimen 5G +/+: postnatal adult (more

)
Note: Double labeled: green - Cldn1; blue - DAPI.

Structure	Level	Pattern	Image	Note
TS28: back skin	Present		5G +/+

5G tm1a/tm1a ©

Specimen 5G (Early): postnatal adult; Krt76^{tm1a(KOMP)Wtsi}/Krt76^{tm1a(KOMP)Wtsi} (more

)
Note: Double labeled: green - Cldn1; blue - DAPI.

Structure	Level	Pattern	Image	Note
TS28: back skin	Present	Regionally restricted	5G tm1a/tm1a	Authors report mislocalization of membranous expression.

S2E +/+ ©

Specimen S2E +/+: postnatal adult (more

)
Note: Double labeled: red - Cldn1; blue - DAPI.

Structure	Level	Pattern	Image	Note
TS28: metapodial pad epidermis	Present		S2E +/+

S2E No wound ©

Specimen S2E No wound: postnatal adult; Krt76^{tm1a(KOMP)Wtsi}/Krt76^{tm1a(KOMP)Wtsi} (more

)
Note: Double labeled: red - Cldn1; blue - DAPI.

Structure	Level	Pattern	Image	Note
TS28: metapodial pad epidermis	Present		S2E No wound

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23