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Gene Expression Data
Assay Details
Assay
Reference: J:231734 Winkle CC, et al., Trim9 Deletion Alters the Morphogenesis of Developing and Adult-Born Hippocampal Neurons and Impairs Spatial Learning and Memory. J Neurosci. 2016 May 4;36(18):4940-58
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6451779
Gene symbol: Gfap
Gene name: glial fibrillary acidic protein
Antibody: anti-Gfap (ab7260)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 5B +/+: postnatal week 5; Mapttm2Arbr/Mapt+, Neurod6tm1(cre)Kan/Neurod6+ (more )
Note: Conditional mutant. vibratome section
Structure Level Pattern Image Note
TS28: hippocampus Present 5B upper left , 5B upper right
Specimen 5B fl/fl: postnatal week 5; Mapttm2Arbr/Mapt+, Neurod6tm1(cre)Kan/Neurod6+, Trim9tm1Slgu/Trim9tm1Slgu (more )
Note: Conditional mutant. vibratome section
Structure Level Pattern Image Note
TS28: hippocampus Present 5B lower left , 5B lower right No major neuroanatomical defects.
Specimen 5C +/+: postnatal week 5; Mapttm2Arbr/Mapt+, Neurod6tm1(cre)Kan/Neurod6+ (more )
Note: Conditional mutant. vibratome section
Structure Level Pattern Image Note
TS28: hippocampus Present 5C upper left , 5C upper right
Specimen 5C fl/fl: postnatal week 5; Mapttm2Arbr/Mapt+, Neurod6tm1(cre)Kan/Neurod6+, Trim9tm1Slgu/Trim9tm1Slgu (more )
Note: Conditional mutant. vibratome section
Structure Level Pattern Image Note
TS28: hippocampus Present 5C lower right , 5C lower left Aberrant projections into the septal nuclei.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory