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Gene Expression Data
Assay Details
Assay
Reference: J:223183 Yang T, et al., Analysis of PRICKLE1 in human cleft palate and mouse development demonstrates rare and common variants involved in human malformations. Mol Genet Genomic Med. 2014 Mar;2(2):138-51
Assay type: RNA in situ
MGI Accession ID: MGI:6449680
Gene symbol: Prickle1
Gene name: prickle planar cell polarity protein 1
Probe: Prickle1 cDNA3
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf Strong Graded 4A There is strong expression in the posterior palate and weak expression in the anterior palate.
Specimen 4A': embryonic day 13.5 (more )
Note: anterior coronal section
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Weak 4A' Weak expression is seen in the anterior palate.
Specimen 4A'': embryonic day 13.5 (more )
Note: posterior coronal section
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Strong 4A'' Strong expression is seen in the posterior palate.
Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: palatal shelf Strong Graded There is strong expression in the posterior palate and weak expression in the anterior palate.
Specimen 4B: embryonic day 13.5; Prickle1m2Ingm/Prickle1m2Ingm (more )
Structure Level Pattern Image Note
TS21: palatal shelf Weak 4B Expression is downregulated in the mutant.
Specimen 4B': embryonic day 13.5; Prickle1m2Ingm/Prickle1m2Ingm (more )
Note: anterior coronal section
Structure Level Pattern Image Note
TS21: palatal shelf Weak 4B' Expression is downregulated in the mutant.
Specimen 4B'': embryonic day 13.5; Prickle1m2Ingm/Prickle1m2Ingm (more )
Note: posterior coronal section
Structure Level Pattern Image Note
TS21: palatal shelf Weak 4B'' Expression is downregulated in the mutant.
Specimen 7E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: face Strong 7E Expression is seen in the external maxillary processes that will develop into cheeks and mouth. If it is expressed in the palate at this stage, it is below the level of detection of this assay.
Specimen 7F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch maxillary component Present 7F Expression is seen in the internal maxilla process.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory