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Gene Expression Data
Assay Details
Assay
Reference: J:200791 Wakaoka T, et al., Tracing Sox10-expressing cells elucidates the dynamic development of the mouse inner ear. Hear Res. 2013 Aug;302:17-25
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6438101
Gene symbol: Sox10
Gene name: SRY (sex determining region Y)-box 10
Reporter: GFP
Direct Detection
Results
Specimen 1A: embryonic day 8.5; Sox10tm1Takk/Sox10+ (more )
Structure Level Pattern Image Note
TS13: otic placode Absent 1A At this time, expression in the ectoderm next to the hindbrain, which corresponds to otic placode, was unclear.
Specimen 1B: embryonic day 8.75; Sox10tm1Takk/Sox10+ (more )
Structure Level Pattern Image Note
TS13: otic placode Absent 1B At this time, expression in the ectoderm next to the hindbrain, which corresponds to otic placode, was unclear.
Specimen 1C: embryonic day 9.0; Sox10tm1Takk/Sox10+ (more )
Structure Level Pattern Image Note
TS14: otic placode Strong 1C
Specimen 1D: embryonic day 9.25; Sox10tm1Takk/Sox10+ (more )
Structure Level Pattern Image Note
TS15: otocyst Present 1D
Specimen 1E: embryonic day 9.5; Sox10tm1Takk/Sox10+ (more )
Structure Level Pattern Image Note
TS15: otocyst Present 1E
Specimen 1F: embryonic day 10.5; Sox10tm1Takk/Sox10+ (more )
Structure Level Pattern Image Note
TS17: inner ear Present Widespread 1F
TS17: cranial nerve Present 1F Expression is seen in cranial and peripheral nerves.
TS17: peripheral nerve trunk Present 1F Expression is seen in cranial and peripheral nerves.
Specimen 2A: embryonic day 9.5; Sox10tm1Takk/Sox10+ (more )
Structure Level Pattern Image Note
TS15: otocyst Present Widespread 2A
Specimen 2B: embryonic day 10.5; Sox10tm1Takk/Sox10+ (more )
Structure Level Pattern Image Note
TS17: otocyst Present 2B Areas of expression include the endolymphatic duct and vertical canal plate.
Specimen 2C: embryonic day 11.5; Sox10tm1Takk/Sox10+ (more )
Structure Level Pattern Image Note
TS19: otocyst Present Widespread 2C Areas of expression include the cochlea and vertical canal plate.
Specimen 2D: embryonic day 12.5; Sox10tm1Takk/Sox10+ (more )
Structure Level Pattern Image Note
TS20: semicircular canal Present 2D Expression is seen in the superior and lateral semicircular canals.
TS20: superior semicircular canal Present 2D Expression is seen in the superior and lateral semicircular canals.
TS20: cochlea Present 2D
TS20: inner ear Present 2D Areas of expression include the endolymphatic duct.
Specimen 2E: embryonic day 13.5; Sox10tm1Takk/Sox10+ (more )
Structure Level Pattern Image Note
TS21: posterior semicircular canal Present 2E
TS21: superior semicircular canal Present 2E
TS21: saccule Present 2E
TS21: utricle Present 2E
TS21: cochlea Present 2E
Specimen 2F: embryonic day 14.5; Sox10tm1Takk/Sox10+ (more )
Structure Level Pattern Image Note
TS22: endolymphatic duct Present 2F
TS22: saccule Present 2F
TS22: utricle Present 2F
Specimen 2G: embryonic day 16.5; Sox10tm1Takk/Sox10+ (more )
Structure Level Pattern Image Note
TS24: endolymphatic sac Present 2G
TS24: semicircular canal Present 2G Expression is seen in the anterior, lateral and posterior ampulla.
TS24: saccule Present 2G
TS24: utricle Present 2G
Specimen 2H: postnatal day 1; Sox10tm1Takk/Sox10+ (more )
Structure Level Pattern Image Note
TS27: endolymphatic sac Present 2H
TS27: crista ampullaris Present 2H Expression is present in the anterior and posterior ampulla.
TS27: vestibular ganglion inferior part Present 2H
Specimen 2I: postnatal day 1; Sox10tm1Takk/Sox10+ (more )
Structure Level Pattern Image Note
TS27: cochlear ganglion Present 2J , 2I
TS27: cochlea epithelium Present 2I , 2J
TS27: vestibulocochlear nerve cochlear component Present 2I
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory