About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:230169 Isaac J, et al., DLX3 regulates bone mass by targeting genes supporting osteoblast differentiation and mineral homeostasis in vivo. Cell Death Differ. 2014 Sep;21(9):1365-76
Assay type: RT-PCR
MGI Accession ID: MGI:6437534
Gene symbol: Tnfrsf11b
Gene name: tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
Probe: Opg-pE, Opg-pF
Assay notes: Quantitative RT-PCR normalized to beta-actin expression. Fold change is shown relative to wild type.
Results Image: 4E OPG
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex Note
WT P w 5 TS28: femur metaphysis Present Not Specified Not Specified Male
Dlx3OCN-cKO P w 5 TS28: femur metaphysis Present (a) Not Specified involves: FVB/NJ Dlx3tm3Mso/Dlx3tm3Mso, Tg(BGLAP-cre)1Clem/0Male Conditional mutant.
WT P w 5 TS28: femur diaphysis Present Not Specified Not Specified Male
Dlx3OCN-cKO P w 5 TS28: femur diaphysis Present (b) Not Specified involves: FVB/NJ Dlx3tm3Mso/Dlx3tm3Mso, Tg(BGLAP-cre)1Clem/0Male Conditional mutant.
Notes:
(a) Expression in the metaphysis of this mutant is the same as in wild-type.
(b) Expression in the diaphysis has increased 3.6 fold in this mutant compared to wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory