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Gene Expression Data
Assay Details
Assay
Reference: J:97372 Henion TR, et al., Beta1,3-N-acetylglucosaminyltransferase 1 glycosylation is required for axon pathfinding by olfactory sensory neurons. J Neurosci. 2005 Feb 23;25(8):1894-903
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6437504
Gene symbol: Or10a4
Gene name: olfactory receptor family 10 subfamily A member 4
Reporter: lacZ
Antibody: anti-B-galactosidase (CR7001)
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 5a E18 beta-3GnT1+/-: embryonic day 18.0; B3gnt2Gt(KST308)Byg/B3gnt2+, Or10a4tm1Mom/Or10a4+ (more )
Structure Level Pattern Image Note
TS26: main olfactory bulb glomerular layer Present 5a E18 beta-3GnT1+/-
TS26: main olfactory bulb olfactory nerve layer Present 5a E18 beta-3GnT1+/-
Specimen 5a E18 beta-3GnT1-/-: embryonic day 18.0; B3gnt2Gt(KST308)Byg/B3gnt2Gt(KST308)Byg, Or10a4tm1Mom/Or10a4+ (more )
Structure Level Pattern Image Note
TS26: main olfactory bulb olfactory nerve layer Present 5a E18 beta-3GnT1-/- Immunopositive axons fail to grow through the nerve layer into the glomerular layer in the mutant.
TS26: main olfactory bulb glomerular layer Absent 5a E18 beta-3GnT1-/-
Specimen 5a PD10 beta-3GnT1+/-: postnatal day 10; B3gnt2Gt(KST308)Byg/B3gnt2+, Or10a4tm1Mom/Or10a4+ (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Present 5a PD10 beta-3GnT1+/-
Specimen 5a PD10 beta-3GnT1-/-: postnatal day 10; B3gnt2Gt(KST308)Byg/B3gnt2Gt(KST308)Byg, Or10a4tm1Mom/Or10a4+ (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb olfactory nerve layer Absent 5a PD10 beta-3GnT1-/- No labeled axons were detected in the mutant nerve layer, indicating that axons reaching the olfactory bulb at P1 were not maintained.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory