Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Mavsem1Smoc
Name:	mitochondrial antiviral signaling protein; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI ID:	MGI:6430641
Gene:	Mavs  Location: Chr2:131075983-131089945 bp, + strand  Genetic Position: Chr2, 63.3 cM
Alliance:	Mavsem1Smoc page

Strain of Origin:

C57BL/6J

Allele Type:    Endonuclease-mediated (Null/knockout) Mutation:    Intragenic deletion     CRISPR/Cas9 genome editing technology was used to delete exons 2-3 of the gene. (J:238766)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Mavs Mutation:	36 strains or lines available

Original:	J:280922 Zhu W, et al., TRAF3IP3 mediates the recruitment of TRAF3 to MAVS for antiviral innate immunity. EMBO J. 2019 Sep 16;38(18):e102075
All:	3 reference(s)