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Gene Expression Data
Assay Details
Assay
Reference: J:173839 Bertrand N, et al., Hox genes define distinct progenitor sub-domains within the second heart field. Dev Biol. 2011 May 15;353(2):266-74
Assay type: RNA in situ
MGI Accession ID: MGI:6430418
Gene symbol: Hoxa1
Gene name: homeobox A1
Probe: Hoxa1 probe11
Probe preparation: Antisense labelled with fluorescein RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1E: embryonic day 7.75 (more )
Note: Double labeled: orange - Hoxa1; blue - Tbx5 (assay MGI:6430433).
Structure Level Pattern Image Note
TS12: embryo mesoderm Present Regionally restricted 1E Expression in domain adjacent to cardiogenic region marked by Tbx5.
TS12: endocardial tube Absent 1E No expression in heart tube.

Specimen 1F: embryonic day 7.75 (more )
Note: Double labeled: orange - Hoxa1; blue - Isl1 (assay MGI:6430434).
Structure Level Pattern Image Note
TS12: cardiogenic splanchnic mesoderm Present Regionally restricted 1F Small overlap between expression domains of Hoxa1 and Isl1 in splanchnic mesoderm.
TS12: secondary heart field Present Regionally restricted 1F Expression in posterior region of second heart field.

Specimen S2B: embryonic day 8.5 (more )
Note: Double labeled: orange - Hoxa1; blue - Isl1 (assay MGI:6430434).
Structure Level Pattern Image Note
TS13: secondary heart field Present Regionally restricted S2B
TS13: endocardial tube Absent S2B No expression in heart tube.

Specimen S2B': embryonic day 8.5 (more )
Note: Double labeled: orange - Hoxa1; blue - Isl1 (assay MGI:6430434).
Structure Level Pattern Image Note
TS13: cardiogenic splanchnic mesoderm Present Regionally restricted S2B' Co-expression with Isl1 in splanchnic mesoderm.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory