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Gene Expression Data
Assay Details
Assay
Reference: J:241694 Gingras J, et al., Synaptic transmission is impaired at neuronal autonomic synapses in agrin-null mice. Dev Neurobiol. 2007 Apr;67(5):521-34
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6416301
Gene symbol: Syp
Gene name: synaptophysin
Antibody: anti-synaptophysin (clone SVP-38)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1a wild type: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: superior cervical ganglion Present 1a upper left Expressed in nerve terminals.
Specimen 1a z+ agrin -/-: embryonic day 18.5; Agrntm1Jrs/Agrntm1Jrs (more )
Structure Level Pattern Image Note
TS26: superior cervical ganglion Present 1a upper middle Expressed in nerve terminals.
Specimen 1a AGD -/-: embryonic day 18.5; Agrntm3Jrs/Agrntm3Jrs (more )
Structure Level Pattern Image Note
TS26: superior cervical ganglion Present 1a upper right Expressed in nerve terminals.
Specimen 2a wild type: embryonic day 18.5 (more )
Note: Double labeled: green - Syp; red - Chrnb2 (assay MGI:6416326) and Chrnb4 (assay MGI:6416327).
Structure Level Pattern Image Note
TS26: superior cervical ganglion Present 2a upper right , 2a upper left Expressed in nerve terminals.
Specimen 2a AGD-/-: embryonic day 18.5; Agrntm3Jrs/Agrntm3Jrs (more )
Note: Double labeled: green - Syp; red - Chrnb2 (assay MGI:6416326) and Chrnb4 (assay MGI:6416327).
Structure Level Pattern Image Note
TS26: superior cervical ganglion Present 2a lower left , 2a lower right Expressed in nerve terminals, similar level as in the wild type. But the synapse number (coexpressed Syp and Chrnb2/b4) was decreased by 40%.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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