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Gene Expression Data
Assay Details
Assay
Reference: J:224632 Lowe KL, et al., Podoplanin and CLEC-2 drive cerebrovascular patterning and integrity during development. Blood. 2015 Jun 11;125(24):3769-77
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6407116
Gene symbol: Itga2b
Gene name: integrin alpha 2b
Antibody: Rat Anti-Mouse CD41 (Clone MWReg30)
Detection system: Secondary antibody coupled to Alexa Fluor 647
Results
Specimen S3 +/+: embryonic day 14.5 (more )
Note: Triple labeled: red - Itga2b; green - Pecam1 (assay MGI:6407096); blue - Ly76 (assay MGI:6407115).
Structure Level Pattern Image Note
TS22: blood Present S3_top middle , S3_top left , S3_top right Expressed in platelets in blood vessels.

Specimen S3 Clec-2-/-: embryonic day 14.5; Clec1btm1.2Arte/Clec1btm1.2Arte (more )
Note: Triple labeled: red - Itga2b; green - Pecam1 (assay MGI:6407096); blue - Ly76 (assay MGI:6407115).
Structure Level Pattern Image Note
TS22: blood Present S3_bottom middle , S3_bottom right , S3_bottom left Expressed in platelets with Ly76+ red cells in blood vessels and in both the ventricles and parenchyma.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory