Gene Expression Data
Assay Details
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Assay
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Reference:
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J:152494
Behesti H, et al., Loss of Tbx2 delays optic vesicle invagination leading to small optic cups. Dev Biol. 2009 Sep 15;333(2):360-72
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6404543
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Gene symbol:
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Tbx2
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Gene name:
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T-box 2
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Results
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Specimen
1A:
embryonic day 9.5
(more  )
Specimen
1A:
(close  )
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Genetic Background:
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involves: 129 * C57BL/6 * ICR
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: optic vesicle |
Present |
Regionally restricted |
1A
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Expression in distal neuroepithelium of optic vesicle, in close proximity to overlying surface ectoderm, along length of dorso-ventral axis of optic vesicle.
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Specimen
1B:
embryonic day 9.5
(more )
Specimen
1B:
(close )
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Genetic Background:
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involves: 129 * C57BL/6 * ICR
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: optic vesicle |
Present |
Regionally restricted |
1B
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Expression localized to distal optic vesicle (presumptive neural retina).
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Specimen
1C:
embryonic day 11.5
(more )
Specimen
1C:
(close )
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Genetic Background:
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involves: 129 * C57BL/6 * ICR
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: neural retina |
Present |
Regionally restricted |
1C
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Expression restricted to dorsal retina in optic cup.
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Specimen
1D:
embryonic day 11.5
(more )
Specimen
1D:
(close )
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Genetic Background:
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involves: 129 * C57BL/6 * ICR
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
5C:
embryonic day 10.5
(more )
Note: 31 somites
Specimen
5C:
(close )
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Genetic Background:
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129/Sv
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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31 somites
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: optic cup |
Present |
Regionally restricted |
5C
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Expression in dorsal presumptive retina.
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Specimen
5D:
(close )
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Genetic Background:
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involves: 129
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Mutant Allele(s):
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Vsx2or-J/Vsx2or-J
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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31 somites
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: optic cup |
Present |
Regionally restricted |
5D
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Authors report normal expression.
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Specimen
6A:
embryonic day 10.5
(more )
Note: 34 somites
Specimen
6A:
(close )
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Genetic Background:
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involves: 129 * C57BL/6 * ICR
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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34 somites
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: optic cup |
Present |
Regionally restricted |
6A
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Expression in dorsal optic cup.
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Specimen
6B:
(close )
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Genetic Background:
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involves: 129 * C57BL/6 * ICR
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Mutant Allele(s):
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Tbx2tm1Pa/Tbx2tm1Pa
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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34 somites
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: optic cup |
Present |
Regionally restricted |
6B
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Authors state probe recognizes mutant transcript. Expression in dorsal optic cup.
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