Clec14atm1Ygk
Targeted Allele Detail
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Symbol: |
Clec14atm1Ygk |
Name: |
C-type lectin domain family 14, member a; targeted mutation 1, Young-Guen Kwon |
MGI ID: |
MGI:6404416 |
Gene: |
Clec14a Location: Chr12:58311506-58316044 bp, - strand Genetic Position: Chr12, 25.65 cM
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Alliance: |
Clec14atm1Ygk page
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Germline Transmission: |
Earliest citation of germline transmission:
J:239835
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A beta-galactosidase gene and loxP-flanked neomycin selection cassette replaced the entire gene while retaining upstream and downstream regulators through homologous recombination. Western blot analysis confirmed absence of protein in lung lysates.
(J:239835)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Clec14a Mutation: |
32 strains or lines available
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Original: |
J:239835 Lee S, et al., Carbohydrate-binding protein CLEC14A regulates VEGFR-2- and VEGFR-3-dependent signals during angiogenesis and lymphangiogenesis. J Clin Invest. 2017 Feb 01;127(2):457-471 |
All: |
2 reference(s) |
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