About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:150759 Lallemand Y, et al., Msx genes are important apoptosis effectors downstream of the Shh/Gli3 pathway in the limb. Dev Biol. 2009 Jul 15;331(2):189-98
Assay type: RNA in situ
MGI Accession ID: MGI:6404389
Gene symbol: Msx2
Gene name: msh homeobox 2
Results
Specimen 1C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present Regionally restricted 1C

Specimen 1D: embryonic day 11.5; Gli3Xt/Gli3Xt (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present Regionally restricted 1D Expression reduced in anterior domain, more extensive for Msx2 than for Msx1. Apical and posterior domains were not affected.

Specimen 1G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present Regionally restricted 1G

Specimen 1H: embryonic day 11.5; Rr29Hx/Rr29+ (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present Regionally restricted 1H Expression barely detectable in anterior-most region where Shh is ectopically expressed.

Specimen 1K: embryonic day 10.75 (more )
Structure Level Pattern Image Note
TS18: forelimb bud Present Regionally restricted 1K

Specimen 1L: embryonic day 10.75; Shhtm1Amc/Shhtm1Amc (more )
Structure Level Pattern Image Note
TS18: forelimb bud Present Regionally restricted 1L Expression in central region significantly higher than in controls.

Specimen S1C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Present Regionally restricted S1C

Specimen S1D: embryonic day 11.5; Gli3Xt/Gli3Xt (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Present Regionally restricted S1D Expression reduced anteriorly, more extensive for Msx2 than for Msx1. Apical and posterior domains were not affected.

Specimen S1G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Present Regionally restricted S1G

Specimen S1H: embryonic day 11.5; Rr29Hx/Rr29+ (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Present Regionally restricted S1H Expression barely detectable in anterior-most region where Shh is ecoptically expressed.

Specimen S1K: embryonic day 10.75 (more )
Structure Level Pattern Image Note
TS18: hindlimb bud Present Regionally restricted S1K Expression lower in central domain of limb bud.

Specimen S1L: embryonic day 10.75; Shhtm1Amc/Shhtm1Amc (more )
Structure Level Pattern Image Note
TS18: hindlimb bud Present Regionally restricted S1L Expression in central region significantly higher than in controls.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/14/2024
MGI 6.23
The Jackson Laboratory