Summary | Transgene origin | Transgene description | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Tg(CAG-DPP4)52Ctkt
Name:	transgene insertion 52, Chien-Te K Tseng
MGI ID:	MGI:6402051
Synonyms:	line 52 hCD26 Tg+
Transgene:	Tg(CAG-DPP4)52Ctkt  Location: unknown
Alliance:	Tg(CAG-DPP4)52Ctkt page

Strain of Origin:

(C57BL/6J x C3H/HeJ)F1 x C57BL/6J

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(CAG-DPP4)52Ctkt expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human DPP4 (1803) Dpp4  (MGI:94919)   Mutation details: The human DPP4 cDNA, the viral receptor of Middle East respiratory-coronavirus (MERS-CoV), generated from the mRNA of human phytohemagglutinin-activated T cells, is under the control of the CAG promoter. (J:258199)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:258199 Agrawal AS, et al., Generation of a transgenic mouse model of Middle East respiratory syndrome coronavirus infection and disease. J Virol. 2015 Apr;89(7):3659-70
All:	13 reference(s)