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Gene Expression Data
Assay Details
Assay
Reference: J:137799 Chauviere M, et al., Disruption of the mitotic kinesin Eg5 gene (Knsl1) results in early embryonic lethality. Biochem Biophys Res Commun. 2008 Aug 8;372(4):513-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6392356
Gene symbol: Kif11
Gene name: kinesin family member 11
Antibody: anti-Eg5 motor
Detection system: Secondary antibody coupled to Texas Red
Results
Specimen 4a A: embryonic day 2.5 (more )
Note: Morula stage embryo. Double labeled with alpha-tubulin (green).
Structure Level Pattern Image Note
TS4: compacted morula Strong Regionally restricted 4a A , 4a C Expression is at the spindle poles with a more discrete decoration of the spindle.
Specimen 4a E: embryonic day 2.5; Kif11tm1Much/Kif11+ (more )
Note: Morula stage embryo. Double labeled with alpha-tubulin (green).
Structure Level Pattern Image Note
TS4: compacted morula Strong Regionally restricted 4a G , 4a E Expression is at the spindle poles with a more discrete decoration of the spindle.
Specimen 4a I: embryonic day 2.5; Kif11tm1Much/Kif11tm1Much (more )
Note: Morula stage embryo. Double labeled with alpha-tubulin (green).
Structure Level Pattern Image Note
TS4: compacted morula Present Regionally restricted 4a I , 4a K Expression is in multiple foci centered on a monopolar spindle.
Specimen 4b WT: embryonic day 2.5 (more )
Note: Morula stage embryo. Double labeled with alpha-tubulin (green).
Structure Level Pattern Image Note
TS4: compacted morula Present Regionally restricted 4b WT Expression is at the spindle poles with a more discrete decoration of the spindle.
Specimen 4b +/-: embryonic day 2.5; Kif11tm1Much/Kif11+ (more )
Note: Morula stage embryo. Double labeled with alpha-tubulin (green).
Structure Level Pattern Image Note
TS4: compacted morula Present Regionally restricted 4b +/- Expression is at the spindle poles with a more discrete decoration of the spindle.
Specimen 4b -/-: embryonic day 2.5; Kif11tm1Much/Kif11tm1Much (more )
Note: Morula stage embryo. Double labeled with alpha-tubulin (green).
Structure Level Pattern Image Note
TS4: compacted morula Present Regionally restricted 4b -/- Expression is in multiple foci centered on a monopolar spindle.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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