About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:137799 Chauviere M, et al., Disruption of the mitotic kinesin Eg5 gene (Knsl1) results in early embryonic lethality. Biochem Biophys Res Commun. 2008 Aug 8;372(4):513-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6392356
Gene symbol: Kif11
Gene name: kinesin family member 11
Antibody: anti-Eg5 motor
Detection system: Secondary antibody coupled to Texas Red
Results
Specimen 4a A: embryonic day 2.5 (more )
Note: Morula stage embryo. Double labeled with alpha-tubulin (green).
Structure Level Pattern Image Note
TS4: compacted morula Strong Regionally restricted 4a A , 4a C Expression is at the spindle poles with a more discrete decoration of the spindle.
Specimen 4a E: embryonic day 2.5; Kif11tm1Much/Kif11+ (more )
Note: Morula stage embryo. Double labeled with alpha-tubulin (green).
Structure Level Pattern Image Note
TS4: compacted morula Strong Regionally restricted 4a G , 4a E Expression is at the spindle poles with a more discrete decoration of the spindle.
Specimen 4a I: embryonic day 2.5; Kif11tm1Much/Kif11tm1Much (more )
Note: Morula stage embryo. Double labeled with alpha-tubulin (green).
Structure Level Pattern Image Note
TS4: compacted morula Present Regionally restricted 4a I , 4a K Expression is in multiple foci centered on a monopolar spindle.
Specimen 4b WT: embryonic day 2.5 (more )
Note: Morula stage embryo. Double labeled with alpha-tubulin (green).
Structure Level Pattern Image Note
TS4: compacted morula Present Regionally restricted 4b WT Expression is at the spindle poles with a more discrete decoration of the spindle.
Specimen 4b +/-: embryonic day 2.5; Kif11tm1Much/Kif11+ (more )
Note: Morula stage embryo. Double labeled with alpha-tubulin (green).
Structure Level Pattern Image Note
TS4: compacted morula Present Regionally restricted 4b +/- Expression is at the spindle poles with a more discrete decoration of the spindle.
Specimen 4b -/-: embryonic day 2.5; Kif11tm1Much/Kif11tm1Much (more )
Note: Morula stage embryo. Double labeled with alpha-tubulin (green).
Structure Level Pattern Image Note
TS4: compacted morula Present Regionally restricted 4b -/- Expression is in multiple foci centered on a monopolar spindle.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory