Gene Expression Data
Assay Details
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Assay
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Reference:
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J:152846
Szabo R, et al., Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice. Development. 2009 Aug;136(15):2653-63
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6392046
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Gene symbol:
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Spint1
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Gene name:
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serine protease inhibitor, Kunitz type 1
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Antibody:
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anti-HAI1
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
3B:
(close  )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Spint2Gt(KST272)Byg/Spint2+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: chorion |
Present |
Regionally restricted |
3B
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Expression is in chorionic and labyrinthine trophoblast cells.
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| TS17: labyrinthine zone |
Present |
Regionally restricted |
3B
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Expression is in chorionic and labyrinthine trophoblast cells.
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| TS17: trophectoderm |
Present |
Regionally restricted |
3B
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Expression is in chorionic and labyrinthine trophoblast cells.
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Specimen
3B':
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Spint2Gt(KST272)Byg/Spint2Gt(KST272)Byg
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: chorion |
Present |
Regionally restricted |
3B'
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Expression is in chorionic and labyrinthine trophoblast cells in the reduced labyrinth of this mutant.
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| TS17: labyrinthine zone |
Present |
Regionally restricted |
3B'
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Expression is in chorionic and labyrinthine trophoblast cells in the reduced labyrinth of this mutant.
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| TS17: trophectoderm |
Present |
Regionally restricted |
3B'
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Expression is in chorionic and labyrinthine trophoblast cells in the reduced labyrinth of this mutant.
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Specimen
5B:
(close )
| Structure |
Level |
Pattern |
Image |
Note |
| TS17: chorion |
Present |
Regionally restricted |
5B
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Expression in this double mutant is restored to levels seen in wild-type embryos.
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| TS17: labyrinthine zone |
Present |
Regionally restricted |
5B
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Expression in this double mutant is restored to levels seen in wild-type embryos.
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| TS17: trophectoderm |
Present |
Regionally restricted |
5B
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Expression in this double mutant is restored to levels seen in wild-type embryos.
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)
Analysis Tools