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Gene Expression Data
Assay Details
Assay
Reference: J:136711 Zhao H, et al., Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation. Dev Biol. 2008 Jun 15;318(2):276-88
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6386992
Gene symbol: Maf
Gene name: MAF bZIP transcription factor
Results
Specimen 6M: embryonic day 12.5; Fgfr1tm1Jpa/Fgfr1tm1Jpa, Fgfr2tm1Dor/Fgfr2tm1Dor, Fgfr3tm1Dor/Fgfr3tm1Dor, Tg(Cryaa-cre)10Mlr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: lens Trace 6M Little expression detected in posterior of mutant lenses.
Specimen 6N: embryonic day 12.5; Fgfr1tm1Jpa/Fgfr1tm1Jpa, Fgfr2tm1Dor/Fgfr2tm1Dor (more )
Structure Level Pattern Image Note
TS21: posterior lens fiber Strong 6N Authors report expression significantly increased in primary fiber cells.
Specimen 6O: embryonic day 16.5; Fgfr1tm1Jpa/Fgfr1tm1Jpa, Fgfr2tm1Dor/Fgfr2tm1Dor, Fgfr3tm1Dor/Fgfr3tm1Dor, Tg(Cryaa-cre)10Mlr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: lens Trace 6O Expression only rarely seen in mutant lenses, likely representing a total reduction in expression rather a failure to accumulate in nuclei.
Specimen 6P: embryonic day 16.5; Fgfr1tm1Jpa/Fgfr1tm1Jpa, Fgfr2tm1Dor/Fgfr2tm1Dor (more )
Structure Level Pattern Image Note
TS24: anterior lens fiber Strong 6P Abundant expression in elongating lens fiber cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory