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Gene Expression Data
Assay Details
Assay
Reference: J:136719 Maretto S, et al., Ventral closure, headfold fusion and definitive endoderm migration defects in mouse embryos lacking the fibronectin leucine-rich transmembrane protein FLRT3. Dev Biol. 2008 Jun 1;318(1):184-93
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6386964
Gene symbol: Flrt3
Gene name: fibronectin leucine rich transmembrane protein 3
Reporter: lacZ
Direct Detection
Assay notes: Fixative was 2.5% glutaraldehyde, 2% paraformaldehyde, 0.1% picric acid.
Results
Specimen 3A: embryonic day 6.5; Flrt3tm1Rob/Flrt3+ (more )
Structure Level Pattern Image Note
TS9: anterior visceral endoderm Present 3A
TS9: extraembryonic component Present Regionally restricted 3A Expression is in the chorion.

Specimen 3B: embryonic day 7.0; Flrt3tm1Rob/Flrt3+ (more )
Structure Level Pattern Image Note
TS10: anterior visceral endoderm Present 3B
TS10: extraembryonic component Present Regionally restricted 3B Expression is in the chorion.
TS10: ectoderm Absent 3B

Specimen 3B': embryonic day 7.0; Flrt3tm1Rob/Flrt3+ (more )
Structure Level Pattern Image Note
TS10: anterior visceral endoderm Present 3B'
TS10: extraembryonic component Present Regionally restricted 3B' Expression is in the chorion.
TS10: ectoderm Absent 3B'

Specimen 3C: embryonic day 7.5; Flrt3tm1Rob/Flrt3+ (more )
Structure Level Pattern Image Note
TS11: definitive endoderm Present Regionally restricted 3C Expression is in the nascent definitive endoderm underlying the forming headfolds.
TS11: neural ectoderm Present Regionally restricted 3C Expression is at the lateral edges of the anterior neurectoderm.
TS11: anterior visceral endoderm Present 3C
TS11: node Present 3C

Specimen 3C': embryonic day 7.5; Flrt3tm1Rob/Flrt3+ (more )
Structure Level Pattern Image Note
TS11: definitive endoderm Present Regionally restricted 3C' Expression is in the nascent definitive endoderm underlying the forming headfolds.
TS11: neural ectoderm Present Regionally restricted 3C' Expression is at the lateral edges of the anterior neurectoderm.
TS11: node Present 3C'

Specimen 3D: embryonic day 8.5; Flrt3tm1Rob/Flrt3+ (more )
Structure Level Pattern Image Note
TS13: trunk Strong Regionally restricted 3D Expression is in the ventral body wall.
TS13: cardiac muscle tissue Strong 3D
TS13: neural ectoderm Present Regionally restricted 3D Expression is in the dorsal edges of the neurectoderm.
TS13: foregut diverticulum Present 3D
TS13: future midbrain Present 3D
TS13: notochord Present 3D
TS13: otic placode Present 3D
TS13: somite Present 3D

Specimen 3D': embryonic day 8.5; Flrt3tm1Rob/Flrt3+ (more )
Structure Level Pattern Image Note
TS13: neural ectoderm Strong Regionally restricted 3D' Expression is in the dorsal edges of the neurectoderm.

Specimen 3E: embryonic day 8.5; Flrt3tm1Rob/Flrt3+ (more )
Structure Level Pattern Image Note
TS13: trunk Strong Regionally restricted 3E Expression is in the ventral body wall.
TS13: cardiac muscle tissue Strong 3E
TS13: neural ectoderm Present Regionally restricted 3E Expression is in the dorsal edges of the neurectoderm.
TS13: foregut diverticulum Present 3E
TS13: future midbrain Present 3E
TS13: notochord Present 3E
TS13: otic placode Present 3E
TS13: somite Present 3E

Specimen 3E': embryonic day 8.5; Flrt3tm1Rob/Flrt3+ (more )
Structure Level Pattern Image Note
TS13: trunk Strong Regionally restricted 3E' Expression is in the ventral body wall.
TS13: cardiac muscle tissue Strong 3E'
TS13: neural ectoderm Strong Regionally restricted 3E' Expression is in the dorsal edges of the neurectoderm.
TS13: foregut diverticulum Strong 3E'
TS13: future midbrain Strong 3E'
TS13: notochord Strong 3E'
TS13: otic placode Strong 3E'
TS13: surface ectoderm Strong 3E'

Specimen 3F: embryonic day 9.5; Flrt3tm1Rob/Flrt3+ (more )
Structure Level Pattern Image Note
TS15: future midbrain Strong 3F
TS15: gut Strong 3F
TS15: hepatic primordium Strong 3F
TS15: optic vesicle Strong 3F
TS15: proepicardium Strong 3F
TS15: sinus venosus Strong 3F

Specimen 3F': embryonic day 9.5; Flrt3tm1Rob/Flrt3+ (more )
Structure Level Pattern Image Note
TS15: future midbrain Strong 3F'
TS15: optic vesicle Strong 3F'

Specimen 3F'': embryonic day 9.5; Flrt3tm1Rob/Flrt3+ (more )
Structure Level Pattern Image Note
TS15: gut Strong 3F''
TS15: proepicardium Strong 3F''
TS15: somite Strong 3F''

Specimen 3F''': embryonic day 9.5; Flrt3tm1Rob/Flrt3+ (more )
Structure Level Pattern Image Note
TS15: gut endoderm Strong 3F'''
TS15: hepatic primordium Strong 3F'''
TS15: sinus venosus Strong 3F'''
TS15: somite Strong 3F'''


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory