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Gene Expression Data
Assay Details
Assay
Reference: J:130196 Alfonsi F, et al., LIFR beta plays a major role in neuronal identity determination and glial differentiation in the mouse facial nucleus. Dev Biol. 2008 Jan 1;313(1):267-78
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6382052
Gene symbol: Etv1
Gene name: ets variant 1
Antibody: anti-ER81
Results
Specimen E14.5 +/+ not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: facial nucleus Present Quanitification of expressing cells is presented in Figure 5I.

Specimen E14.5 -/- not shown: embryonic day 14.5; Lifrtm1Imx/Lifrtm1Imx (more )
Structure Level Pattern Image Note
TS22: facial nucleus Strong Considerable increase in number of expressing cells compared to wild type.

Specimen 5A: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: facial nucleus Present Regionally restricted 5A Expression domain extended into facial nucleus.

Specimen 5B: embryonic day 16.5; Lifrtm1Imx/Lifrtm1Imx (more )
Structure Level Pattern Image Note
TS24: facial nucleus Strong Regionally restricted 5B Expression domain expanded toward a medial position. Considerable increase in number of expressing cells compared to wild type.

Specimen 5C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: facial nucleus Present 5C Expression domain extended into facial nucleus.

Specimen 5D: embryonic day 18.5; Lifrtm1Imx/Lifrtm1Imx (more )
Structure Level Pattern Image Note
TS26: facial nucleus Strong Regionally restricted 5D Expression domain expanded toward a medial position. Considerable increase in number of expressing cells compared to wild type.

Specimen 5K: embryonic day 16.5 (more )
Note: Triple labeled: green - ER81 (Etv1) protein; blue - Isl1 protein (assay MGI:6382044); red - Lhx4 protein (assay MGI:6382056).
Structure Level Pattern Image Note
TS24: facial nucleus Present Regionally restricted 5K Expression domain extended into facial nucleus.

Specimen 5L: embryonic day 16.5; Lifrtm1Imx/Lifrtm1Imx (more )
Note: Triple labeled: green - ER81 (Etv1) protein; blue - Isl1 protein (assay MGI:6382044); red - Lhx4 protein (assay MGI:6382056).
Structure Level Pattern Image Note
TS24: facial nucleus Strong Regionally restricted 5L Considerable increase in number of expressing cells compared to wild type. Expression in Isl1-expressing cells in mutant that do not express ER81 in wild type. No co-expression with Lhx4.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory