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Gene Expression Data
Assay Details
Assay
Reference: J:174215 Chen Y, et al., Plasticity of neural crest-placode interaction in the developing visceral nervous system. Dev Dyn. 2011 Aug;240(8):1880-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6381628
Gene symbol: Sox10
Gene name: SRY (sex determining region Y)-box 10
Antibody: anti-Sox10
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2E: embryonic day 9.5 (more )
Note: Double labeled: green - Sox10; red - Phox2b (assay MGI:6381438).
Structure Level Pattern Image Note
TS15: facio-acoustic preganglion complex Present 2E
TS15: 2nd branchial groove Present Regionally restricted 2E Expression is in cells that stream from rhombomere 4 to the second branchial cleft.
TS15: head mesenchyme derived from neural crest Present Regionally restricted 2E Expression is in cells that stream from rhombomere 4 to the second branchial cleft.
TS15: rhombomere 4 Present Regionally restricted 2E Expression is in cells that stream from rhombomere 4 to the second branchial cleft.
Specimen 2F: embryonic day 9.5; Hoxa1tm3.1Mrc/Hoxa1tm3.1Mrc, Hoxb1tm3Mrc/Hoxb1tm3Mrc (more )
Note: Double labeled: green - Sox10; red - Phox2b (assay MGI:6381438).
Structure Level Pattern Image Note
TS15: facio-acoustic preganglion complex Present 2F Ganglia are fused in this mutant.
TS15: 2nd branchial groove Present Regionally restricted 2F Expression is in cells that stream from rhombomere 2 to the second branchial cleft.
TS15: head mesenchyme derived from neural crest Present Regionally restricted 2F Expression is in cells that stream from rhombomere 2 to the second branchial cleft.
TS15: rhombomere 2 Present Regionally restricted 2F Expression is in cells that stream from rhombomere 2 to the second branchial cleft.
Specimen 3A: embryonic day 12.5 (more )
Note: Double labeled: green - Sox10; red - Phox2b (assay MGI:6381438).
Structure Level Pattern Image Note
TS20: facial ganglion Present 3C , 3A
TS20: otic ganglion Present 3C , 3A
Specimen 3B: embryonic day 12.5; Hoxa1tm3.1Mrc/Hoxa1tm3.1Mrc, Hoxb1tm3Mrc/Hoxb1tm3Mrc (more )
Note: Double labeled: green - Sox10; red - Phox2b (assay MGI:6381438).
Structure Level Pattern Image Note
TS20: facial ganglion Present Regionally restricted 3B , 3D
TS20: otic ganglion Present Regionally restricted 3B , 3D
TS20: head mesenchyme derived from neural crest Present Regionally restricted 3D , 3B Expression is in a stream of cells from the geniculate ganglion into the area normally occupied by the otic ganglion.
Specimen 3G: embryonic day 11.5 (more )
Note: Double labeled: green - Sox10; red - Phox2b (assay MGI:6381438).
Structure Level Pattern Image Note
TS19: autonomic ganglion Present Regionally restricted 3G , 3I Expression is in the sphenopalatine and otic ganglia.
TS19: facial ganglion Present 3I , 3G
TS19: head mesenchyme derived from neural crest Present 3I , 3G
Specimen 3H: embryonic day 11.5; Hoxa1tm3.1Mrc/Hoxa1tm3.1Mrc, Hoxb1tm3Mrc/Hoxb1tm3Mrc (more )
Note: Double labeled: green - Sox10; red - Phox2b (assay MGI:6381438).
Structure Level Pattern Image Note
TS19: autonomic ganglion Present Regionally restricted 3H , 3J Expression is in the sphenopalatine and otic ganglia.
TS19: facial ganglion Present 3J , 3H
TS19: head mesenchyme derived from neural crest Present 3J , 3H
Specimen 4A: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxa3tm1(cre)Moon/Hoxa3+ (more )
Note: Conditional mutant. Triple labeled: blue - Sox10; red - Phox2b (assay MGI:6381438); green - Cre reporter.
Structure Level Pattern Image Note
TS20: sphenopalatine ganglion Present 4A
Specimen 4B: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Triple labeled: blue - Sox10; red - Phox2b (assay MGI:6381438); green - Cre reporter.
Structure Level Pattern Image Note
TS20: sphenopalatine ganglion Present 4B
Specimen 4C: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxa3tm1(cre)Moon/Hoxa3+ (more )
Note: Conditional mutant. Triple labeled: blue - Sox10; red - Phox2b (assay MGI:6381438); green - Cre reporter.
Structure Level Pattern Image Note
TS20: submandibular ganglion Present 4C
Specimen 4D: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Triple labeled: blue - Sox10; red - Phox2b (assay MGI:6381438); green - Cre reporter.
Structure Level Pattern Image Note
TS20: submandibular ganglion Present 4D
Specimen 4E: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxa3tm1(cre)Moon/Hoxa3+ (more )
Note: Conditional mutant. Triple labeled: blue - Sox10; red - Phox2b (assay MGI:6381438); green - Cre reporter.
Structure Level Pattern Image Note
TS20: facial ganglion Present 4E
TS20: otic ganglion Present 4E
Specimen 4F: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxb1tm6(cre)Mrc/Hoxb1+ (more )
Note: Conditional mutant. Triple labeled: blue - Sox10; red - Phox2b (assay MGI:6381438); green - Cre reporter.
Structure Level Pattern Image Note
TS20: facial ganglion Present 4F
TS20: otic ganglion Present 4F
Specimen 4G: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxa3tm1(cre)Moon/Hoxa3+ (more )
Note: Conditional mutant. Triple labeled: blue - Sox10; red - Phox2b (assay MGI:6381438); green - Cre reporter.
Structure Level Pattern Image Note
TS20: otic ganglion Present 4G
Specimen 4H: embryonic day 12.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Hoxa3tm1(cre)Moon/Hoxa3+, Neurog2tm1Fgu/Neurog2tm1Fgu (more )
Note: Conditional mutant. Triple labeled: blue - Sox10; red - Phox2b (assay MGI:6381438); green - Cre reporter.
Structure Level Pattern Image Note
TS20: otic ganglion Present 4H
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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