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Gene Expression Data
Assay Details
Assay
Reference: J:130185 Ellsworth BS, et al., Mechanisms underlying pituitary hypoplasia and failed cell specification in Lhx3-deficient mice. Dev Biol. 2008 Jan 1;313(1):118-29
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6380638
Gene symbol: Tle3
Gene name: transducin-like enhancer of split 3
Antibody: anti-TLE3
Detection system: rhodamine
Results
Specimen 2C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: adenohypophysis pars intermedia Present 2C Expression in prospective intermediate lobe
TS22: adenohypophysis pars anterior Present Scattered 2C Some scattered expression in anterior lobe and periluminal area.
Specimen 2D: embryonic day 14.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd (more )
Structure Level Pattern Image Note
TS22: pituitary gland Present Regionally restricted 2D Grossly normal expression at E14.5.
Specimen 2E: embryonic day 16.5 (more )
Note: Double labeled: green - Tle3; red - Pomc (assay MGI:6380637).
Structure Level Pattern Image Note
TS24: adenohypophysis pars intermedia Present 2E Expression in prospective intermediate lobe
TS24: adenohypophysis pars anterior Present Scattered 2E Some scattered expression in anterior lobe and periluminal area.
Specimen 2E inset: embryonic day 16.5 (more )
Note: Double labeled: green - Tle3; red - Pomc (assay MGI:6380637).
Structure Level Pattern Image Note
TS24: adenohypophysis Present Regionally restricted 2E inset Majority of Tle3-expressing cells also express Pomc.
Specimen 2F: embryonic day 16.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd (more )
Note: Double labeled: green - Tle3; red - Pomc (assay MGI:6380637).
Structure Level Pattern Image Note
TS24: pituitary gland Present Regionally restricted 2F Grossly normal expression at E16.5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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