Igf1r RT-PCR Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:225886 de Iriarte Rodriguez R, et al., Age-regulated function of autophagy in the mouse inner ear. Hear Res. 2015 Dec;330(Pt A):39-50
Assay type:	RT-PCR
MGI Accession ID:	MGI:6378559
Gene symbol:	Igf1r
Gene name:	insulin-like growth factor I receptor

Probe:	Mm00802831_m1
Assay notes:	This assay is a quantitative RT-PCR. Rn18s was used as the standard. Data was not shown and summarized in Table 2 as fold-change of the level in null versus wild type mice.

Results

	Sample Information		Bands	Other Sample Information
Lane	Age	Structure	Size Not Specified (a)	Amount	Genetic Background	Mutant Allele(s)	Sex
E18.5 WT	E18.5	TS26: cochlea	Present	Not Specified	involves: 129S/SvEv * MF1		Not Specified
E18.5 -/-	E18.5	TS26: cochlea	Present (b)	Not Specified	involves: 129S/SvEv * MF1	Igf1^tm1Arge/Igf1^tm1Arge	Not Specified
P30-60 WT	P30-60	TS28: cochlea	Present	Not Specified	involves: 129S/SvEv * MF1		Not Specified
P30-60 -/-	P30-60	TS28: cochlea	Present (c)	Not Specified	involves: 129S/SvEv * MF1	Igf1^tm1Arge/Igf1^tm1Arge	Not Specified
P270 WT	P270	TS28: cochlea	Present	Not Specified	involves: 129S/SvEv * MF1		Not Specified
P270 -/-	P270	TS28: cochlea	Present (d)	Not Specified	involves: 129S/SvEv * MF1	Igf1^tm1Arge/Igf1^tm1Arge	Not Specified
P365 WT	P365	TS28: cochlea	Present	Not Specified	involves: 129S/SvEv * MF1		Not Specified
P365 -/-	P365	TS28: cochlea	Present (e)	Not Specified	involves: 129S/SvEv * MF1	Igf1^tm1Arge/Igf1^tm1Arge	Not Specified

Notes:
(a) Wild type showed a significant decrease (0.79-, 0.56- and a 0.12-fold decrease between E18.5 and P30-60, P270 or P365, respectively) and lower expression levels than in adult null.
(b) Null versus wild-type: 1.09+/-0.09.
(c) Null versus wild-type: 2.06+/-0.16.
(d) Null versus wild-type: 2.88+/-0.21.
(e) Null versus wild-type: 0.72+/-0.18.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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