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Gene Expression Data
Assay Details
Assay
Reference: J:195050 Wilson CL, et al., Endothelial deletion of ADAM17 in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults. Mech Dev. 2013 Apr-May;130(4-5):272-89
Assay type: Western blot
MGI Accession ID: MGI:6378197
Gene symbol: Vcan
Gene name: versican
Results
Image: 6A ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex Note
Adam17Fl/+ E12.5 TS20: heart Present involves: C57BL/6 Adam17tm1.1Rain/Adam17+Not Specified
Adam17Fl/+ E12.5 TS20: heart Present involves: C57BL/6 Adam17tm1.1Rain/Adam17+Not Specified
Adam17Fl/+ E12.5 TS20: heart Present involves: C57BL/6 Adam17tm1.1Rain/Adam17+Not Specified
Tie2-Cre/+;Adam17Fl/+ E12.5 TS20: heart Present involves: C57BL/6 Adam17tm1.1Rain/Adam17+, Tg(Tek-cre)12Flv/0Not Specified Conditional mutant.
Tie2-Cre/+;Adam17Fl/+ E12.5 TS20: heart Present involves: C57BL/6 Adam17tm1.1Rain/Adam17+, Tg(Tek-cre)12Flv/0Not Specified Conditional mutant.
Tie2-Cre/+;Adam17Fl/deltaEx5 E12.5 TS20: heart Weak (a) B6.Cg-Adam17tm1.1Rain Adam17tm1.2Rain Tg(Tek-cre)12Flv Adam17tm1.1Rain/Adam17tm1.2Rain, Tg(Tek-cre)12Flv/0Not Specified Conditional mutant.
Tie2-Cre/+;Adam17Fl/deltaEx5 E12.5 TS20: heart Weak (a) B6.Cg-Adam17tm1.1Rain Adam17tm1.2Rain Tg(Tek-cre)12Flv Adam17tm1.1Rain/Adam17tm1.2Rain, Tg(Tek-cre)12Flv/0Not Specified Conditional mutant.
Tie2-Cre/+;Adam17Fl/deltaEx5 E12.5 TS20: heart Weak (a) B6.Cg-Adam17tm1.1Rain Adam17tm1.2Rain Tg(Tek-cre)12Flv Adam17tm1.1Rain/Adam17tm1.2Rain, Tg(Tek-cre)12Flv/0Not Specified Conditional mutant.
Notes:
(a) Compared to controls, the conditional mutant hearts showed dramatically reduced levels of versican.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
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