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Gene Expression Data
Assay Details
Assay
Reference: J:38379 Xu PX, et al., Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in lens and nasal placode. Development. 1997 Jan;124(1):219-31
Assay type: RNA in situ
MGI Accession ID: MGI:6377517
Gene symbol: Eya1
Gene name: EYA transcriptional coactivator and phosphatase 1
Probe: Eya1 cDNA8
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 6A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: telencephalon Present Regionally restricted 6A Expression is in the cerebral cortex and the septum and is weak in the ganglionic eminence.
TS19: cartilage condensation Present 6A
TS19: forebrain ventricular layer Present 6A
TS19: genital tubercle Present 6A
TS19: gut Present 6A
TS19: hindbrain ventricular layer Present 6A
TS19: limb Present 6A
TS19: metanephros Present 6A
TS19: olfactory epithelium Present 6A
TS19: vertebral pre-cartilage condensation Present 6A
TS19: hindbrain Present 6A Expression includes motor neurons in the hindbrain.
TS19: tongue Present Regionally restricted 6A Expression is in the intrinsic and extrinsic muscles of the tongue.
TS19: oral region Present Regionally restricted 6A Expression is in dental mesenchyme.
TS19: head mesenchyme Present Regionally restricted 6A Expression is in craniofacial mesenchyme.
TS19: Rathke's pouch Weak 6A
TS19: eye Weak 6A
TS19: facial ganglion Weak 6A
TS19: future spinal cord Weak 6A
TS19: neural tube floor plate Weak 6A
TS19: optic recess Weak 6A
TS19: optic stalk Weak 6A
TS19: vagus nerve Weak 6A
TS19: brain Weak Regionally restricted 6A Expression is in the choroid plexus.
TS19: diencephalon Weak Regionally restricted 6A Expression is in the hypothalamus.

Specimen 6C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cartilage condensation Present 6C
TS20: cerebral cortex Present 6C
TS20: forebrain ventricular layer Present 6C
TS20: genital tubercle Present 6C
TS20: gut Present 6C
TS20: limb Present 6C
TS20: metanephros Present 6C
TS20: olfactory epithelium Present 6C
TS20: vertebral cartilage condensation Present 6C
TS20: vibrissa follicle Present 6C
TS20: telencephalon Present Regionally restricted 6C Expression is in the septum.
TS20: hindbrain Present 6C Expression includes motor neurons in the hindbrain.
TS20: tongue muscle Present Regionally restricted 6C Expression is in the intrinsic and extrinsic muscles of the tongue.
TS20: jaw Present Regionally restricted 6C Expression is in dental mesenchyme.
TS20: head mesenchyme Strong Regionally restricted 6C Expression is in craniofacial mesenchyme.
TS20: choroid plexus Weak 6C
TS20: eye Weak 6C
TS20: facial ganglion Weak 6C
TS20: ganglionic eminence Weak 6C
TS20: hypothalamus Weak 6C
TS20: optic stalk Weak 6C
TS20: remnant of Rathke's pouch Weak 6C
TS20: spinal cord floor plate Weak 6C
TS20: vagus nerve Weak 6C
TS20: diencephalon Weak Regionally restricted 6C Expression is in the optic recess.
TS20: spinal cord Weak Regionally restricted 6C Expression is dorsal.

Specimen 6E left: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: genital tubercle Strong 6E left
TS20: metanephros Strong 6E left
TS20: cartilage condensation Present 6E left
TS20: cerebral cortex Present 6E left
TS20: forebrain ventricular layer Present 6E left
TS20: gut Present 6E left
TS20: hindbrain ventricular layer Present 6E left
TS20: limb Present 6E left
TS20: olfactory epithelium Present 6E left
TS20: vertebral cartilage condensation Present 6E left
TS20: vibrissa follicle Present 6E left
TS20: telencephalon Present Regionally restricted 6E left Expression is in the septum.
TS20: hindbrain Present 6E left Expression includes motor neurons in the hindbrain.
TS20: tongue muscle Present Regionally restricted 6E left Expression is in the intrinsic and extrinsic muscles of the tongue.
TS20: jaw Present Regionally restricted 6E left Expression is in dental mesenchyme.
TS20: head mesenchyme Strong Regionally restricted 6E left Expression is in craniofacial mesenchyme.
TS20: choroid plexus Weak 6E left
TS20: eye Weak 6E left
TS20: facial ganglion Weak 6E left
TS20: ganglionic eminence Weak 6E left
TS20: hypothalamus Weak 6E left
TS20: optic stalk Weak 6E left
TS20: remnant of Rathke's pouch Weak 6E left
TS20: spinal cord Weak 6E left
TS20: spinal cord floor plate Weak 6E left
TS20: vagus nerve Weak 6E left
TS20: diencephalon Weak Regionally restricted 6E left Expression is in the optic recess.

Specimen 6E right: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: genital tubercle Strong 6E right
TS20: metanephros Strong 6E right
TS20: cartilage condensation Present 6E right
TS20: cerebral cortex Present 6E right
TS20: forebrain ventricular layer Present 6E right
TS20: gut Present 6E right
TS20: hindbrain ventricular layer Present 6E right
TS20: limb Present 6E right
TS20: olfactory epithelium Present 6E right
TS20: vertebral cartilage condensation Present 6E right
TS20: vibrissa follicle Present 6E right
TS20: telencephalon Present Regionally restricted 6E right Expression is in the septum.
TS20: hindbrain Present 6E right Expression includes motor neurons in the hindbrain.
TS20: tongue muscle Present Regionally restricted 6E right Expression is in the intrinsic and extrinsic muscles of the tongue.
TS20: jaw Present Regionally restricted 6E right Expression is in dental mesenchyme.
TS20: head mesenchyme Strong Regionally restricted 6E right Expression is in craniofacial mesenchyme.
TS20: choroid plexus Weak 6E right
TS20: eye Weak 6E right
TS20: facial ganglion Weak 6E right
TS20: ganglionic eminence Weak 6E right
TS20: hypothalamus Weak 6E right
TS20: optic stalk Weak 6E right
TS20: remnant of Rathke's pouch Weak 6E right
TS20: spinal cord Weak 6E right
TS20: spinal cord floor plate Weak 6E right
TS20: vagus nerve Weak 6E right
TS20: diencephalon Weak Regionally restricted 6E right Expression is in the optic recess.

Specimen 7A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: vibrissa follicle Present Regionally restricted 7A Expression is in the condensed mesenchyme surrounding the developing whisker follicle.

Specimen 7C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: vertebral cartilage condensation Present 7C

Specimen 7E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: stomach mesenchyme Present Graded 7E Expression is dorsoventral.

Specimen 8A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: optic stalk Strong 8A
TS19: lens vesicle Present 8A
TS19: pigmented retinal epithelium Present 8A
TS19: retina Present Regionally restricted 8A Expression is in the peripheral retinal margin.
TS19: neural retina Weak 8A

Specimen 8B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lens vesicle Present 8B
TS20: optic stalk Present 8B
TS20: pigmented retinal epithelium Present 8B
TS20: retina Present Regionally restricted 8B Expression is in the peripheral retinal margin.
TS20: neural retina Weak 8B

Specimen 8C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lens anterior epithelium Strong 8C
TS22: lens Present 8C
TS22: optic stalk Present 8C
TS22: pigmented retinal epithelium Present 8C
TS22: retina Present Regionally restricted 8C Expression is in the peripheral retinal margin.
TS22: lens fiber Weak 8C
TS22: neural retina Weak 8C

Specimen 9A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: nose Strong Regionally restricted 9A Expression is in the nasal capsule.
TS20: nasal septum Strong 9A
TS20: olfactory epithelium Strong 9A

Specimen 9C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: nasal capsule Strong 9C
TS22: nasal septum Strong 9C
TS22: olfactory epithelium Strong Uniform 9C

Specimen 9E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: nasal capsule Strong 9E
TS24: nasal septum Strong 9E
TS24: olfactory epithelium Strong Regionally restricted 9E Expression is in the apical epithelial layer and is weak or absent in the basal epithelial layer.

Specimen 10A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: lens placode Present 10A
TS15: olfactory placode Present 10A

Specimen 10B: embryonic day 9.5; Pax6Sey-Neu/Pax6Sey-Neu (more )
Structure Level Pattern Image Note
TS15: lens placode Weak 10B
TS15: olfactory placode Weak 10B

Specimen not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cornea Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory