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Gene Expression Data
Assay Details
Assay
Reference: J:169193 Walsh T, et al., Genomic duplication and overexpression of TJP2/ZO-2 leads to altered expression of apoptosis genes in progressive nonsyndromic hearing loss DFNA51. Am J Hum Genet. 2010 Jul 9;87(1):101-9
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6376155
Gene symbol: Tjp2
Gene name: tight junction protein 2
Antibody: ZO-2 Antibody (#2847)
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 3C upper: embryonic day 16.5 (more )
Note: Double labeled: red - Tjp2; green - Myo6 (assay MGI:6376157).
Structure Level Pattern Image Note
TS24: cochlea epithelium Present 3C upper right , 3C upper left Expressed mainly at cell junctions and also in the cytoplasm and nuclei of hair cells and adjacent supporting cells.
Specimen 3C middle: postnatal day 0 (more )
Note: Double labeled: red - Tjp2; green - Myo6 (assay MGI:6376157).
Structure Level Pattern Image Note
TS27: cochlea epithelium Present 3C middle left , 3C middle right Expressed mainly at cell junctions and also in the cytoplasm and nuclei of hair cells and adjacent supporting cells.
Specimen 3D: embryonic day 16.5 (more )
Note: Double labeled: red - Tjp2; green - Myo6 (assay MGI:6376157).
Structure Level Pattern Image Note
TS24: saccule epithelium Present 3D left , 3D right Expressed mainly at cell junctions and also in the cytoplasm and nuclei of hair cells and adjacent supporting cells.
Specimen not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: utricle epithelium Present Expressed mainly at cell junctions and also in the cytoplasm and nuclei of hair cells and adjacent supporting cells.
TS24: semicircular canal epithelium Present Regionally restricted Expressed in the crista. Expressed mainly at cell junctions and also in the cytoplasm and nuclei of hair cells and adjacent supporting cells.
Specimen not shown: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: crista ampullaris Present Expressed mainly at cell junctions and also in the cytoplasm and nuclei of hair cells and adjacent supporting cells.
TS27: utricle epithelium Present Expressed mainly at cell junctions and also in the cytoplasm and nuclei of hair cells and adjacent supporting cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory