Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Terb2em1Leim
Name:	telomere repeat binding bouquet formation protein 2; endonuclease-mediated mutation 1, Ming Lei
MGI ID:	MGI:6362934
Synonyms:	Terb2Y56E
Gene:	Terb2  Location: Chr2:122016753-122036874 bp, + strand  Genetic Position: Chr2, 60.56 cM, cytoband F1
Alliance:	Terb2em1Leim page

Strain of Origin:

C57BL/6

Allele Type:    Endonuclease-mediated (Null/knockout) Mutation:    Nucleotide substitutions   Mutation details: CRISPR-targeting produced the amino acid substitution of glutamic acid for tyrosine at position 56 (Y56E). (J:270644)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Terb2 Mutation:	10 strains or lines available

Original:	J:270644 Wang Y, et al., The meiotic TERB1-TERB2-MAJIN complex tethers telomeres to the nuclear envelope. Nat Commun. 2019 Feb 4;10(1):564
All:	1 reference(s)