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Gene Expression Data
Assay Details
Assay
Reference: J:74155 Kagoshima M, et al., Diverse gene expression and function of semaphorins in developing lung: positive and negative regulatory roles of semaphorins in lung branching morphogenesis. Genes Cells. 2001 Jun;6(6):559-71
Assay type: RNA in situ
MGI Accession ID: MGI:6361498
Gene symbol: Sema3f
Gene name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
Probe: Sema3F probe6
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: lung epithelium Weak Regionally restricted 1G Weak expression in distal portion of epithelium. Higher expression in distal end of bronchial trees than in lobar bronchi.
TS19: lung mesenchyme Weak Regionally restricted 1G Weak expression in surrounding mesenchyme.
Specimen 1H: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lung epithelium Weak Regionally restricted 1H Weak expression in distal portion of epithelium. Higher expression in distal end of bronchial trees than in lobar bronchi.
TS21: lung mesenchyme Weak Regionally restricted 1H Weak expression in surrounding mesenchyme.
Specimen 1I: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lung epithelium Weak Regionally restricted 1I Weak expression in distal portion of epithelium. Higher expression in distal end of bronchial trees than in lobar bronchi.
TS21: lung mesenchyme Weak Regionally restricted 1I Weak expression in surrounding mesenchyme.
Specimen 2E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lung epithelium Strong Regionally restricted 2E Abundunt expression in epithelial lining cells of terminal buds.
TS23: lung mesenchyme Weak Diffuse 2E
Specimen 2F: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lung epithelium Strong Regionally restricted 2F Abundunt expression in epithelial lining cells of terminal buds.
TS23: lung mesenchyme Weak Diffuse 2F
Specimen 3E: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: bronchiole epithelium Present 3E Mild to moderate expression in epithelium of lobar bronchi and bronchioles.
TS25: lobar bronchus epithelium Present 3E Mild to moderate expression in epithelium of lobar bronchi and bronchioles.
TS25: lung mesenchyme Weak Diffuse 3E
Specimen 3F: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: bronchiole epithelium Present 3F Mild to moderate expression in epithelium of lobar bronchi and bronchioles.
TS25: lobar bronchus epithelium Present 3F Mild to moderate expression in epithelium of lobar bronchi and bronchioles.
TS25: lung mesenchyme Weak Diffuse 3F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory