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Gene Expression Data
Assay Details
Assay
Reference: J:29949 Hurlin PJ, et al., Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation. EMBO J. 1995 Nov 15;14(22):5646-59
Assay type: RNA in situ
MGI Accession ID: MGI:6361314
Gene symbol: Mxd4
Gene name: Max dimerization protein 4
Probe: mad4 probe1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 6F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 6F Strongest expression in differentiating cells of intermediate zone at ventral part of neural tube. Weak expression in ventricular zone.
Specimen E11.5 not shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: neural tube Present Regionally restricted Authors report expression similar to 10.5 pc. Highly expressed in intermediate zone; Reduced level of expression in ventricular zone mostly persists in dorsal part of neural tube.
Specimen E12.5 not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted Authors report expression similar to 10.5 pc. Highly expressed in intermediate zone; Reduced level of expression in ventricular zone mostly persists in dorsal part of neural tube.
Specimen E14.5 not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: spinal cord Present Widespread Expression throughout spinal cord.
TS22: epidermis Absent
Specimen 7G: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: dermis Present 7G
TS25: hair follicle Present 7G
TS25: epidermis Present Regionally restricted 7G Expression in some differentiating cells in upper layers of epidermis.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory