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Gene Expression Data
Assay Details
Assay
Reference: J:275842 Garnai SJ, et al., Variants in myelin regulatory factor (MYRF) cause autosomal dominant and syndromic nanophthalmos in humans and retinal degeneration in mice. PLoS Genet. 2019 May;15(5):e1008130
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6360311
Gene symbol: Arr3
Gene name: arrestin 3, retinal
Antibody: Anti-Cone Arrestin (AB15282)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 6D/E left: postnatal day 22 (more )
Structure Level Pattern Image Note
TS28: photoreceptor layer inner segment Present 6D/E left Expressed in the cones.
TS28: photoreceptor layer outer segment Present 6D/E left Expressed in the cones.
TS28: retina outer nuclear layer Present 6D/E left Expressed in the cones.

Specimen 6D/E middle: postnatal day 22; Myrftm1Barr/Myrf+, Tg(rx3-icre)1Mjam/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: photoreceptor layer inner segment Present 6D/E middle Expressed in the cones.
TS28: photoreceptor layer outer segment Present 6D/E middle Expressed in the cones.
TS28: retina outer nuclear layer Present 6D/E middle Expressed in the cones.

Specimen 6D/E right: postnatal day 22; Myrftm1Barr/Myrftm1Barr, Tg(rx3-icre)1Mjam/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: retina outer nuclear layer Present 6D/E right Expressed in the cones.
TS28: photoreceptor layer inner segment Present 6D/E right Expressed in the cones. Significant loss of this area compared to total retinal area.
TS28: photoreceptor layer outer segment Present 6D/E right Expressed in the cones. Significant loss of this area compared to total retinal area.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory