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Gene Expression Data
Assay Details
Assay
Reference: J:104160 Tole S, et al., Development of midline cell types and commissural axon tracts requires Fgfr1 in the cerebrum. Dev Biol. 2006 Jan 1;289(1):141-51
Assay type: RNA in situ
MGI Accession ID: MGI:6356623
Gene symbol: Tbr1
Gene name: T-box brain transcription factor 1
Probe: Tbr1 probe7
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen S2D control: embryonic day 17.5; Fgfr1tm1Upir/? (more )
Structure Level Pattern Image Note
TS25: neocortex Present Regionally restricted S2D control Expression in layer 6.
TS25: cerebral cortex subventricular zone Present S2D control Expression in subplate neurons as well as in the subventricular zone.
TS25: cortical subplate Present S2D control Expression in subplate neurons as well as in the subventricular zone.
Specimen S2D Fgfr1+/-: embryonic day 17.5; Fgfr1tm1Upir/Fgfr1+, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: neocortex Present Regionally restricted S2D Fgfr1+/- Authors report normal expression in heterozygous and homozygous mutants.
TS25: cerebral cortex subventricular zone Present S2D Fgfr1+/- Authors report normal expression in heterozygous and homozygous mutants.
TS25: cortical subplate Present S2D Fgfr1+/- Authors report normal expression in heterozygous and homozygous mutants.
Specimen S2D Fgfr1-/-: embryonic day 17.5; Fgfr1tm1Upir/Fgfr1tm1Upir, Foxg1tm1(cre)Skm/Foxg1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: neocortex Present Regionally restricted S2D Fgfr1-/- Authors report normal expression in heterozygous and homozygous mutants.
TS25: cerebral cortex subventricular zone Present S2D Fgfr1-/- Authors report normal expression in heterozygous and homozygous mutants.
TS25: cortical subplate Present S2D Fgfr1-/- Authors report normal expression in heterozygous and homozygous mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory