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Gene Expression Data
Assay Details
Assay
Reference: J:266809 Hino K, et al., Comparative Analysis of cul5 and rbx2 Expression in the Developing and Adult Murine Brain and Their Essentiality During Mouse Embryogenesis. Dev Dyn. 2018 Nov;247(11):1227-1236
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6342837
Gene symbol: Rnf7
Gene name: ring finger protein 7
Reporter: lacZ
Direct Detection
Results
Specimen 5A E16.5: embryonic day 16.5; Rnf7tm1a(EUCOMM)Wtsi/Rnf7+ (more )
Structure Level Pattern Image Note
TS24: main olfactory bulb mitral cell layer Strong 5A E16.5
TS24: main olfactory bulb prospective granule cell layer Absent 5A E16.5
Specimen 5A P0: postnatal day 0; Rnf7tm1a(EUCOMM)Wtsi/Rnf7+ (more )
Structure Level Pattern Image Note
TS27: main olfactory bulb mitral cell layer Strong 5A P0
TS27: main olfactory bulb granule cell layer Present 5A P0
Specimen 5A AD: postnatal day 60-90; Rnf7tm1a(EUCOMM)Wtsi/Rnf7+ (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb mitral cell layer Strong 5A AD
TS28: main olfactory bulb granule cell layer Present 5A AD
Specimen 5B E16.5: embryonic day 16.5; Rnf7tm1a(EUCOMM)Wtsi/Rnf7+ (more )
Structure Level Pattern Image Note
TS24: cerebral cortex marginal layer Present 5B E16.5
TS24: cerebral cortex subventricular zone Present 5B E16.5
TS24: cerebral cortex ventricular layer Present 5B E16.5
Specimen 5B P0: postnatal day 0; Rnf7tm1a(EUCOMM)Wtsi/Rnf7+ (more )
Structure Level Pattern Image Note
TS27: cerebral cortex marginal zone Present 5B P0
TS27: cortical plate Present 5B P0
TS27: cortical layer I Strong Uniform 5B P0
TS27: cortical layer II Strong Uniform 5B P0
TS27: cortical layer III Strong Uniform 5B P0
TS27: cortical layer IV Strong Uniform 5B P0
TS27: cortical layer V Strong Uniform 5B P0
TS27: cortical layer VI Strong Uniform 5B P0
Specimen 5B AD: postnatal day 60-90; Rnf7tm1a(EUCOMM)Wtsi/Rnf7+ (more )
Structure Level Pattern Image Note
TS28: cortical layer I Strong Uniform 5B AD
TS28: cortical layer II Strong Uniform 5B AD
TS28: cortical layer III Strong Uniform 5B AD
TS28: cortical layer IV Strong Uniform 5B AD
TS28: cortical layer V Strong Uniform 5B AD
TS28: cortical layer VI Strong Uniform 5B AD
Specimen 5C E16.5: embryonic day 16.5; Rnf7tm1a(EUCOMM)Wtsi/Rnf7+ (more )
Structure Level Pattern Image Note
TS24: hippocampus ventricular layer Present 5C E16.5
TS24: hippocampus Present Regionally restricted 5C E16.5 Expressed in the stratum pyramidale.
Specimen 5C P0: postnatal day 0; Rnf7tm1a(EUCOMM)Wtsi/Rnf7+ (more )
Structure Level Pattern Image Note
TS27: dentate gyrus Present 5C P0
TS27: hippocampus Present 5C P0 Expression pattern mimiced that of Cul5.
Specimen 5C AD: postnatal day 60-90; Rnf7tm1a(EUCOMM)Wtsi/Rnf7+ (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Present 5C AD Highest expression.
TS28: hippocampus Present 5C AD Expression pattern mimiced that of Cul5.
Specimen 5D E16.5: embryonic day 16.5; Rnf7tm1a(EUCOMM)Wtsi/Rnf7+ (more )
Structure Level Pattern Image Note
TS24: forebrain Present Ubiquitous 5D E16.5
Specimen 5D P0: postnatal day 0; Rnf7tm1a(EUCOMM)Wtsi/Rnf7+ (more )
Structure Level Pattern Image Note
TS27: forebrain Present Ubiquitous 5D P0
Specimen 5D AD: postnatal day 60-90; Rnf7tm1a(EUCOMM)Wtsi/Rnf7+ (more )
Structure Level Pattern Image Note
TS28: forebrain Present Ubiquitous 5D AD
Specimen 5E E14.5: embryonic day 14.5; Rnf7tm1a(EUCOMM)Wtsi/Rnf7+ (more )
Structure Level Pattern Image Note
TS22: cerebellum layer Present Regionally restricted 5E E14.5 Expressed in Purkinje cells.
TS22: deep cerebellar nucleus Present 5E E14.5
TS22: medulla oblongata Present 5E E14.5
Specimen 5E P0: postnatal day 0; Rnf7tm1a(EUCOMM)Wtsi/Rnf7+ (more )
Structure Level Pattern Image Note
TS27: cerebellum Purkinje cell layer Present 5E P0
TS27: deep cerebellar nucleus Present 5E P0
TS27: medulla oblongata Present 5E P0
Specimen 5E AD: postnatal day 60-90; Rnf7tm1a(EUCOMM)Wtsi/Rnf7+ (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong 5E AD
TS28: cerebellum internal granule cell layer Strong 5E AD
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory