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Gene Expression Data
Assay Details
Assay
Reference: J:34068 Constam DB, et al., SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis. J Cell Biol. 1996 Jul;134(1):181-91
Assay type: RNA in situ
MGI Accession ID: MGI:6323630
Gene symbol: Pcsk5
Gene name: proprotein convertase subtilisin/kexin type 5
Probe: SPC6 cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 5A/B/C/D: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: amnion Strong 5A/B Most intense.
TS11: extraembryonic endoderm Strong 5A/B Most intense.
TS11: primitive endoderm Strong Regionally restricted 5A/B , 5C/D Most intense in the nascent mesoderm located in the distal region of the primitive streak.

Specimen 5E: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: somite Strong 5E
TS13: yolk sac Strong 5E

Specimen 5F: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: dermomyotome Strong 5F

Specimen 5G/H: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cranium bone primordium Present 5G/H Increased expression.
TS20: tongue muscle Present 5G/H Increased expression.

Specimen 5I: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: vertebral cartilage condensation Present 5I Increased expression.

Specimen 6E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Strong 6E
TS19: hindlimb bud mesenchyme Present Regionally restricted 6E Expressed in the mesenchyme underlying the apical ectodermal ridge, although at significantly lower levels.

Specimen 7E/F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb digit mesenchyme Present Regionally restricted 7E/F Expressed in the condensing mesenchymal cells surrounding the cartilage primordia of the future digits. More abundant in dorsal compared to ventral mesenchyme.

Specimen 7G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb digit mesenchyme Present Regionally restricted 7G Expressed in the distal region, more abundant in dorsal compared to ventral mesenchyme.

Specimen 8G/H: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: intestinal villus Strong Regionally restricted 8G/H Expressed in the epithelial cells of the villi but not in the mesenchyme.

Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: decidua Present Regionally restricted Expressed at the site of fusion of the two decidual lobes.

Specimen not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: forelimb bud presumptive apical ectodermal ridge Strong


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory