Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Tnfrsf25tm1.1Rsie
Name:	tumor necrosis factor receptor superfamily, member 25; targeted mutation 1, Richard Siegel
MGI ID:	MGI:6316350
Synonyms:	DR3 FL
Gene:	Tnfrsf25  Location: Chr4:152200391-152204576 bp, + strand  Genetic Position: Chr4, 82.89 cM, cytoband E1
Alliance:	Tnfrsf25tm1.1Rsie page

Germline Transmission:	Earliest citation of germline transmission: J:257626
Parent Cell Line:	ART B6 3.6 (ES Cell)
Strain of Origin:	C57BL/6NTac

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: The targeting vector is designed to insert loxP sites flanking exons 1-5 of the gene, and an FRT-flanked neomycin selection cassette. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:257626)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tnfrsf25 Mutation:	24 strains or lines available

Original:	J:257626 Ferdinand JR, et al., Cleavage of TL1A Differentially Regulates Its Effects on Innate and Adaptive Immune Cells. J Immunol. 2018 Feb 15;200(4):1360-1369
All:	1 reference(s)