Mki67 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:233378 Barazzuol L, et al., Low levels of endogenous or X-ray-induced DNA double-strand breaks activate apoptosis in adult neural stem cells. J Cell Sci. 2015 Oct 1;128(19):3597-606
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6316334
Gene symbol:	Mki67
Gene name:	antigen identified by monoclonal antibody Ki 67

Antibody:	Anti-Ki67 (SolA15; 14-5698-82)
Detection system:	Secondary antibody coupled to Alexa Fluor 594

Results

Specimen adult WT: postnatal adult (more

)
Note: This data represents specimens in cell count graphs reported in Fig. 3.

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex subventricular zone	Present
TS28: dentate gyrus subgranular zone	Present

Specimen adult Atm-/-: postnatal adult; Atm^tm1Awb/Atm^tm1Awb (more

)
Note: This data represents specimens in cell count graphs reported in Fig. 3.

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex subventricular zone	Present
TS28: dentate gyrus subgranular zone	Present

Specimen adult Lig4^Y288C: postnatal adult; Lig4^tiny/Lig4^tiny (more

)
Note: This data represents specimens in cell count graphs reported in Fig. 3.

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex subventricular zone	Present
TS28: dentate gyrus subgranular zone	Present

Specimen adult Atm-/-; Lig4^Y288C: postnatal adult; Atm^tm1Awb/Atm^tm1Awb, Lig4^tiny/Lig4^tiny (more

)
Note: This data represents specimens in cell count graphs reported in Fig. 3.

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex subventricular zone	Present

3E WT ©

Specimen 3E WT: postnatal adult (more

)
Note: Double labeled: red - Mki67; green - Trp53bp1 (assay MGI:6316062).

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex subventricular zone	Present		3E WT

3E Atm-/- ©

Specimen 3E Atm-/-: postnatal adult; Atm^tm1Awb/Atm^tm1Awb (more

)
Note: Double labeled: red - Mki67; green - Trp53bp1 (assay MGI:6316062).

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex subventricular zone	Present		3E Atm-/-

3E Lig4^Y288C ©

Specimen 3E Lig4^Y288C: postnatal adult; Lig4^tiny/Lig4^tiny (more

)
Note: Double labeled: red - Mki67; green - Trp53bp1 (assay MGI:6316062).

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex subventricular zone	Present		3E Lig4^Y288C

5B WT ©

Specimen 5B WT: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex subventricular zone	Present	Regionally restricted	5B WT	Ventral subventricular zone.

5B Atm-/- ©

Specimen 5B Atm-/-: postnatal adult; Atm^tm1Awb/Atm^tm1Awb (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex subventricular zone	Present	Regionally restricted	5B Atm-/-	Ventral subventricular zone.

5B Lig4^Y288C ©

Specimen 5B Lig4^Y288C: postnatal adult; Lig4^tiny/Lig4^tiny (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex subventricular zone	Present	Regionally restricted	5B Lig4^Y288C	Ventral subventricular zone.

5B Atm-/-; Lig4^Y288C ©

Specimen 5B Atm-/-; Lig4^Y288C: postnatal adult; Atm^tm1Awb/Atm^tm1Awb, Lig4^tiny/Lig4^tiny (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex subventricular zone	Present	Regionally restricted	5B Atm-/-; Lig4^Y288C	Ventral subventricular zone.

6C E14.5 ©

Specimen 6C E14.5: embryonic day 14.5; Lig4^tiny/Lig4^tiny (more

)

Structure	Level	Pattern	Image	Note
TS22: neocortex	Present		6C E14.5

6C P5 ©

Specimen 6C P5: postnatal day 5; Lig4^tiny/Lig4^tiny (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex subventricular zone	Present		6C P5

6C P15 ©

Specimen 6C P15: postnatal day 15; Lig4^tiny/Lig4^tiny (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex subventricular zone	Present		6C P15

6E P5 ©

Specimen 6E P5: postnatal day 5 (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex subventricular zone	Present		6E P5

6E P15 ©

Specimen 6E P15: postnatal day 15 (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex subventricular zone	Present		6E P15

Specimen 6E 2/3 months: postnatal month 2-3 (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex subventricular zone	Present		6E 2/3 months

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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