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Shc2em1Adiuj
Endonuclease-mediated Allele Detail
Summary
Symbol: Shc2em1Adiuj
Name: SHC (Src homology 2 domain containing) transforming protein 2; endonuclease-mediated mutation 1, MODEL-AD Center
MGI ID: MGI:6315852
Gene: Shc2  Location: Chr10:79453885-79473752 bp, - strand  Genetic Position: Chr10, 39.72 cM
Alliance: Shc2em1Adiuj page
Mutation
origin
Strain of Origin:  B6(SJL)-Apoetm1.1(APOE*4)Adiuj Trem2em1Adiuj/J
Mutation
description
Allele Type:    Endonuclease-mediated (Not Applicable)
Mutations:    Insertion, Nucleotide substitutions
    CRISPR/Cas9 genome editing is used to introduce a V433M point mutation in to the gene. (J:101977)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Shc2 Mutation:  33 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory