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Gene Expression Data
Assay Details
Assay
Reference: J:253196 Dubail J, et al., Impaired ADAMTS9 secretion: A potential mechanism for eye defects in Peters Plus Syndrome. Sci Rep. 2016 Sep 30;6:33974
Assay type: RNA in situ
MGI Accession ID: MGI:6313387
Gene symbol: Adamts9
Gene name: ADAM metallopeptidase with thrombospondin type 1 motif 9
Probe: Adamts9 probe1
Probe preparation: RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2a E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: retina Strong Regionally restricted 2a E10.5 Strong expression in optic cup, preponderantly in anterior pole of retina.
TS17: lens vesicle Weak 2a E10.5 Weak expression in invaginating lens vesicle
Specimen 2a E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: retina Very strong Regionally restricted 2a E11.5 Authors report strongest expression of all stages analyzed, localized mostly in anterior pole of retina.
Specimen 2a E11.5 (inset): embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: retina Strong Regionally restricted 2a E11.5 (inset) Expression in anterior pole of retina.
TS19: hyaloid vascular plexus Present 2a E11.5 (inset)
TS19: lens vesicle Present 2a E11.5 (inset)
Specimen 2a E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: retina Strong Regionally restricted 2a E12.5 Strong expression persists in anterior pole of retina.
Specimen 2a E12.5 (upper inset): embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: retina Present Regionally restricted 2a E12.5 (upper inset) Expression persists in anterior pole of retina.
TS20: lens vesicle epithelium Present 2a E12.5 (upper inset)
TS20: cornea stroma Present 2a E12.5 (upper inset) Expression in mesenchymal cells within developing cornea.
Specimen 2a E12.5 (lower inset): embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hyaloid vascular plexus Present 2a E12.5 (lower inset)
Specimen 2a E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: retina Strong Regionally restricted 2a E13.5 Strong expression persists in anterior pole of retina.
Specimen 2a E13.5 (upper inset): embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: retina Strong Regionally restricted 2a E13.5 (upper inset) Strong expression persists in anterior pole of retina.
TS21: lens Absent 2a E13.5 (upper inset) After E12.5, expression no longer detected in the lens.
TS21: optic choroid Present 2a E13.5 (upper inset) Expression in choroid and sclera
TS21: cornea stroma Present 2a E13.5 (upper inset) Expression in mesenchymal cells within developing cornea.
Specimen 2a E13.5 (middle inset): embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hyaloid vascular plexus Present Regionally restricted 2a E13.5 (middle inset) Authors report expression in endothelial cells of tunica vasculosa lentis and vasa hyaloidea propria.
Specimen 2a E13.5 (lower inset): embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: retina Present Regionally restricted 2a E13.5 (lower inset)
Specimen 2a P0: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: eye Present Regionally restricted 2a P0 Most strongly expressed in ciliary margin zone and prospective ciliary body, sclera, corneal keratocytes and choroidal vasculature.
Specimen 2a P0 (1st inset): postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cornea Present Regionally restricted 2a P0 (1st inset) Expression in corneal keratinocytes.
Specimen 2a P0 (2nd inset): postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: ciliary body Present 2a P0 (2nd inset) Expression in ciliary margin zone, prospective ciliary body and sclera
TS27: sclera Present 2a P0 (2nd inset) Expression in ciliary margin zone, prospective ciliary body and sclera
Specimen 2a P0 (3rd inset): postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: lens Absent 2a P0 (3rd inset) After E12.5, expression no longer detected in the lens.
TS27: tunica vasculosa lentis Present Regionally restricted 2a P0 (3rd inset) Authors report expression in endothelial cells of tunica vasculosa lentis and vasa hyaloidea propria.
TS27: vasa hyaloidea propria Present Regionally restricted 2a P0 (3rd inset) Authors report expression in endothelial cells of tunica vasculosa lentis and vasa hyaloidea propria.
Specimen 2a P0 (4th inset): postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: retina Ambiguous 2a P0 (4th inset)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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