Adamts9 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:253196 Dubail J, et al., Impaired ADAMTS9 secretion: A potential mechanism for eye defects in Peters Plus Syndrome. Sci Rep. 2016 Sep 30;6:33974
Assay type:	RNA in situ
MGI Accession ID:	MGI:6313387
Gene symbol:	Adamts9
Gene name:	ADAM metallopeptidase with thrombospondin type 1 motif 9

Probe:	Adamts9 probe1
Probe preparation:	RNA
Visualized with:	Alkaline phosphatase

Results

2a E10.5 ©

Specimen 2a E10.5: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: retina	Strong	Regionally restricted	2a E10.5	Strong expression in optic cup, preponderantly in anterior pole of retina.
TS17: lens vesicle	Weak		2a E10.5	Weak expression in invaginating lens vesicle

2a E11.5 ©

Specimen 2a E11.5: embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS19: retina	Very strong	Regionally restricted	2a E11.5	Authors report strongest expression of all stages analyzed, localized mostly in anterior pole of retina.

2a E11.5 (inset) ©

Specimen 2a E11.5 (inset): embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS19: retina	Strong	Regionally restricted	2a E11.5 (inset)	Expression in anterior pole of retina.
TS19: hyaloid vascular plexus	Present		2a E11.5 (inset)
TS19: lens vesicle	Present		2a E11.5 (inset)

2a E12.5 ©

Specimen 2a E12.5: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: retina	Strong	Regionally restricted	2a E12.5	Strong expression persists in anterior pole of retina.

2a E12.5 (upper inset) ©

Specimen 2a E12.5 (upper inset): embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: retina	Present	Regionally restricted	2a E12.5 (upper inset)	Expression persists in anterior pole of retina.
TS20: lens vesicle epithelium	Present		2a E12.5 (upper inset)
TS20: cornea stroma	Present		2a E12.5 (upper inset)	Expression in mesenchymal cells within developing cornea.

2a E12.5 (lower inset) ©

Specimen 2a E12.5 (lower inset): embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: hyaloid vascular plexus	Present		2a E12.5 (lower inset)

2a E13.5 ©

Specimen 2a E13.5: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: retina	Strong	Regionally restricted	2a E13.5	Strong expression persists in anterior pole of retina.

2a E13.5 (upper inset) ©

Specimen 2a E13.5 (upper inset): embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: retina	Strong	Regionally restricted	2a E13.5 (upper inset)	Strong expression persists in anterior pole of retina.
TS21: lens	Absent		2a E13.5 (upper inset)	After E12.5, expression no longer detected in the lens.
TS21: optic choroid	Present		2a E13.5 (upper inset)	Expression in choroid and sclera
TS21: cornea stroma	Present		2a E13.5 (upper inset)	Expression in mesenchymal cells within developing cornea.

2a E13.5 (middle inset) ©

Specimen 2a E13.5 (middle inset): embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: hyaloid vascular plexus	Present	Regionally restricted	2a E13.5 (middle inset)	Authors report expression in endothelial cells of tunica vasculosa lentis and vasa hyaloidea propria.

2a E13.5 (lower inset) ©

Specimen 2a E13.5 (lower inset): embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: retina	Present	Regionally restricted	2a E13.5 (lower inset)

2a P0 ©

Specimen 2a P0: postnatal day 0 (more

)

Structure	Level	Pattern	Image	Note
TS27: eye	Present	Regionally restricted	2a P0	Most strongly expressed in ciliary margin zone and prospective ciliary body, sclera, corneal keratocytes and choroidal vasculature.

Specimen 2a P0 (1st inset): postnatal day 0 (more

)

Structure	Level	Pattern	Image	Note
TS27: cornea	Present	Regionally restricted	2a P0 (1st inset)	Expression in corneal keratinocytes.

Specimen 2a P0 (2nd inset): postnatal day 0 (more

)

Structure	Level	Pattern	Image	Note
TS27: ciliary body	Present		2a P0 (2nd inset)	Expression in ciliary margin zone, prospective ciliary body and sclera
TS27: sclera	Present		2a P0 (2nd inset)	Expression in ciliary margin zone, prospective ciliary body and sclera

Specimen 2a P0 (3rd inset): postnatal day 0 (more

)

Structure	Level	Pattern	Image	Note
TS27: lens	Absent		2a P0 (3rd inset)	After E12.5, expression no longer detected in the lens.
TS27: tunica vasculosa lentis	Present	Regionally restricted	2a P0 (3rd inset)	Authors report expression in endothelial cells of tunica vasculosa lentis and vasa hyaloidea propria.
TS27: vasa hyaloidea propria	Present	Regionally restricted	2a P0 (3rd inset)	Authors report expression in endothelial cells of tunica vasculosa lentis and vasa hyaloidea propria.

Specimen 2a P0 (4th inset): postnatal day 0 (more

)

Structure	Level	Pattern	Image	Note
TS27: retina	Ambiguous		2a P0 (4th inset)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24